Award Data

DESCRIPTION provided by applicant We devised a new generation highly sensitivity method to diagnosis peripheral neuropathy early when the probability for reversal is greatest Cancer chemotherapy and diabetes are the most common causes of neuropathy in the USA Both cause decreased sweating abnormal circulation peripheral numbness pain and weakness If diagnosed early both are potentially ...

DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...

DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

The development and integration of three unique and innovative algorithm prototypes into a"Fused Track and Characterization Schema"are proposed. This Schema will encompass the determination of signatures and characteristics of objects that can be identified by RF and EO/IR Sensors in order to enable multi-sensor data fusion and correlation. The first algorithm, the"3D Pose Estimation"Algorithm, p ...

OptTek Systems, Inc (OptTek), proposes an affordable, effective UQ capability for both legacy and new BMDS M & S. The OptTek Team includes research institution partner Oak Ridge National Laboratory (ORNL) and subcontractor RTSync Corporation (RTSync). The proposed BMDS M & S UQ capability maximizes insertability into existing and future MDA BMDS M & S-supported Event processes, analysis methods, a ...

A goal of Uncertainty Quantification (UQ) is to use computer simulation of complex systems to make scientifically informed assessments for high-consequence decisions. Because end-to-end empirical data is difficult to obtain for the Ballistic Missile Defense System (BMDS), computer simulation provides the best method for understanding BMDS capabilities against a wide range of threats. Numerica Co ...

Antimony containing III-V semiconducting compounds are particularly attractive for the fabrication of a wide variety of electronic and optoelectronic devices such as photo detectors operating in the long wave infrared wavelength (12-32µm) range. The production of epi quality GaSb wafers still remains one of the important problems for rapid commercialization of GaSb devices. Sinmat Inc. proposes a ...

This Phase II effort will further develop a technique to improve current seeker discrimination and tracking capabilities using a unique particle filter algorithm (PFA) approach. The advancement represents a significant upgrade to current and future seekers facing advanced threats in stressing environments. Quantifiable improvements over many facets of the current approach have been realized during ...

Higher efficiency solar cells are needed to reduce mass, volume, and cost of DoD space missions. However, to achieve higher efficiency and radiation hardness of the best to date multi-junction photovoltaic (PV) devices, several challenges must be addressed. This project aims to develop: 1) Quantum Well (QW)-based multi-junction cell that exhibits enhanced efficiency, and 2) Radiation-hardened PV c ...

The Missile Defense Agency (MDA) seeks technical investigations related to the development and application of advanced electronic materials, processes, and devices to meet its need for radiation hardened, high performance electronics for critical space and missile applications. With the advent of smaller transistor dimensions and reductions in price per bit, significant changes in materials and pr ...