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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. rAAV5-hCNGB3 Gene Therapy for Achromatopsia: Safety and Efficacy in a Dog Model

    SBC: APPLIED GENETIC TECHNOLOGIES CORPORATION            Topic: N

    DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A Device to Quantify Sweat of Single Sweat Glands to Diagnose Neuropathy

    SBC: Neuro Devices, Inc.            Topic: 107

    DESCRIPTION provided by applicant We devised a new generation highly sensitivity method to diagnosis peripheral neuropathy early when the probability for reversal is greatest Cancer chemotherapy and diabetes are the most common causes of neuropathy in the USA Both cause decreased sweating abnormal circulation peripheral numbness pain and weakness If diagnosed early both are potentially ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Multi-scale modeling of corrosion fatigue damage using peridynamics theory

    SBC: CFD Research Corporation            Topic: N13AT007

    The overall objective of this effort is to identify, and validate a suitable methodology and the associated multi-scale computational technique for predictive assessment of corrosion fatigue damage in Naval aircraft. Annual costs for corrosion inspection and repair of military aircraft are estimated to exceed $1B. Predictive modeling of corrosion fatigue damage is challenging since it has to captu ...

    STTR Phase I 2013 Department of DefenseNavy
  5. Maneuver Prediction and Avoidance Logic For Unmanned Aircraft System Encounters with Non-Cooperative Air Traffic

    SBC: Numerica Corporation            Topic: N13AT003

    For Unmanned Aircraft Systems (UAS) to operate seamlessly in both the U.S. National Airspace System (NAS) and abroad, it will be crucial that they possess a sense-and-avoid (SAA) capability that can ensure safe operations among maneuvering, non-cooperative aircraft. Numerica Corporation, in partnership with Johns Hopkins University, proposes to develop a set of algorithms to model the uncertaintie ...

    STTR Phase I 2013 Department of DefenseNavy
  6. High Efficiency Computation of High Reynolds Number Flows

    SBC: Technosoft, Inc            Topic: N13AT009

    Although advancements in CFD technology and high performance computing have proven to be effective and reasonably accurate in assessing the hydrodynamic performance of naval vessels, the effort required to develop associated analysis models remains a challenging and time consuming task. Decomposing and manipulating the design geometry for mesh construction, while capturing near-field and far-field ...

    STTR Phase I 2013 Department of DefenseNavy
  7. Mechanical Property Characterization and Modeling for Structural Mo-Si-B Alloys for High Temperature Applications

    SBC: Imaging Systems Technology, Inc.            Topic: N13AT012

    Under this STTR, Imaging Systems Technology (IST) in cooperation with Georgia Institute Technology (GIT) will develop and mature models to predict mechanical properties of refractory alloys with an eye toward tailoring these alloys for specific applications. In particular, this research will focus on addressing core aspects of Integrated Computational Materials Engineering (ICME) as it applies to ...

    STTR Phase I 2013 Department of DefenseNavy
  8. Mechanical Property Characterization and Modeling for Structural Mo-Si-B Alloys for High Temperature Applications

    SBC: Deep Springs Technology            Topic: N13AT012

    The objective of the work described in this proposal is to aid in the advancement of Mo-Si-B alloys for use in high temperature applications such as hot gas stream components in turbine engines. Such alloys are being characterized for their monotonic tensile properties in tension and compression as well for their creep resistance. Likewise, multiphase Mo-Si-B alloys have been studied in terms of m ...

    STTR Phase I 2013 Department of DefenseNavy
  9. Compact robust testbed for cold-atom clock and sensor applications

    SBC: Coldquanta, Inc.            Topic: N13AT018

    As strontium and other alkaline-earth metals become increasingly attractive for ultracold-atom applications, there is a growing need to develop compact, robust systems for cooling, trapping, and studying these elements. In this proposal, ColdQuanta will team with Dr. Jun Ye at JILA and the University of Colorado at Boulder to develop a portable, turn-key system that can produce, utilize, and optic ...

    STTR Phase I 2013 Department of DefenseNavy
  10. Compact, cold-atom clock for Navy field use

    SBC: Vescent Photonics LLC            Topic: N13AT018

    Vescent Photonics proposes to develop a compact laser system and integrate it with a cold-atom micro primary standard developed under the DARPA IMPACT program. In phase I we will investigate performance enhancements resulting from immobilizing the cold-atom sample with an optical lattice formed from an optical field whose wavelength is chosen to minimize the differential light shifts between the s ...

    STTR Phase I 2013 Department of DefenseNavy
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