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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Access to Exercise Stress Testing for Elderly Native Americans in Remote Locations

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: N

    DESCRIPTION provided by applicant Heart disease is the leading cause of death among elderly American Indians and Alaska Natives Heart disease death rates for elderly American Indians at per are percent higher than average in the total U S population Most elderly Native Americans live in remote locations and lack transportation to healthcare facilities This is a key barrie ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. A screening assay for chemicals that affect the differentiation of human neural cells.

    SBC: Nzumbe, Inc.            Topic: NIEHS

    DESCRIPTION provided by applicant Human brain development represents a highly vulnerable time to chemical exposures because immature cells are actively undergoing differentiation into more complex cell types e g neurons astrocytes oligodendroglia to form neural circuits A major reason for this vulnerability is that neuronal differentiation requires critical time dependent changes to the ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Custom Fit 3D-Printed Pediatric Respiratory Masks

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: NICHD

    DESCRIPTION provided by applicant This project will develop an FDA approved process D printing system and advanced D printable material suitable for point of care manufacturing of custom fit continuous positive airway pressure CPAP masks for neonates In extremely low birth weight infants nasal CPAP therapy is delivered via soft biocompatible neonatal sized nasal masks suitable for lon ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Novel Membrane Protein Solubilization/Stabilization Screen

    SBC: SOLUBLE THERAPEUTICS, INC            Topic: 100

    DESCRIPTION provided by applicant The increasing output of new integral membrane protein IMP structures is partially due to the availability of an increasing number of chemical variables such as detergents detergent like molecules lipids and solubilizing stabilizing additives It is clear that specific combinations and concentrations of these different variables are often necessary to impr ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a Novel Therapeutic Approach for Cryptococcal Meningitis

    SBC: Minnetronix Medical, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant When Cryptococcus is manifested as Cryptococcal meningitis CM it creates a large burden of mortality and morbidity to the patient and is very difficult for the clinician to treat There are now US cases and over million cases of CM worldwide annually with estimated deaths of per year CM is caused when Cryptococcus neoformans a basidiomyce ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Development of novel compounds for the treatment of atrial fibrillation

    SBC: Elex Biotech, Inc            Topic: NHLBI

    DESCRIPTION provided by applicant Atrial fibrillation AF is the most prevalent type of cardiac arrhythmia in the developed world affecting million people in the United States alone a number that is expected to double by because of population aging Current pharmacological options are ineffective which may be in part because these drugs fail to target key pathogenic mechanisms Recen ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Directed Antifungal Therapy for HIV-associated Cryptococcal Meningitis

    SBC: Minnetronix Medical, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Directed Antifungal Therapy for HIV associated Cryptococcal Meningitis PI Lad Shivanand and McCabe Aaron Project Summary Cryptococcosis is an important systemic mycosis and one of the most prevalent infectious diseases in human immunodeficiency virus HIV positive individuals Amongst the million people with HIV AIDS recent estimates indicate that there ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Distance Filtering System for Retinal Implants

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: N

    DESCRIPTION provided by applicant We propose to develop and evaluate the utility of a novel input camera system for retinal prosthetics that allows users to filter optical imagery based on distance from the observer We call this andquot depth filteringandquot which can be accomplished with a depth sensing stereoscopic camera system Retinal prostheses can restore partial vision to people bli ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Enhancing Care of the Aged and Dying in Prisons

    SBC: KLEIN BUENDEL, INC            Topic: NIA

    DESCRIPTION provided by applicant The United States has the highest rate of incarceration in the world The demographics of the prison population are shifting In fact the number of sentenced state and federal prisoners age or older grew at times the rate of the overall prison population from The health status of aging inmates does not mirror the free world population In fac ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Identifying activators of interferon regulatory factors for neuroprotection

    SBC: Neuralexo, LLC            Topic: NINDS

    DESCRIPTION provided by applicant Stroke is a leading cause of morbidity and mortality in the United States However less than of patients are eligible for the current approved interventions of tissue plasminogen activator or thrombectomy We seek to develop new therapeutics to reduce the extent of damage and functional impairment resulting from ischemic injury to the brain an area of signi ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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