Award Data

For this Phase I SBIR proposal, Vcom3D proposes to design advanced medical moulage that accurately simulates the progression of an injury or pathology by morphing through a series of clinical states to enable learners to confirm the progression of the wound and to determine whether iatrogenic errors or pathologies occurred duing treatment. The physical morphing moulage may be applied to medical m ...

The metabolic syndrome MetS is a cluster of factors that increases the risks for cardiovascular disease type diabetes mellitus and mortality and currently affects andgt of US adults MetS is associated with endothelial dysfunction decreased circulating endothelial progenitor cells EPCs and a pro inflammatory state We have made the exciting discovery that therapy with allogeneic me ...

Compatibility Between Brain Computer Interface and High Efficiency Augmentative and Alternative Communication Systems ABSTRACT Brain computer interfaces BCI can now enable text production for people who cannot move yet they provide only the simplest communication interfaces and have not been widely adopted Current augmentative and alternative communication AAC systems are widely adopted and ...

Project Summary Diabetic retinopathy DR is a leading cause of vision loss affecting about million people worldwide A major breakthrough in DR therapy is the recent approval of vascular endothelial growth factor VEGF inhibitors However anti VEGF therapy has limited efficacy with a number of side effects The critical barrier is how to identify other angiogenic targets for alternative or ...

Abstract Type Diabetes T D affects an ever growing population While this disease typically has been associated with juveniles the disease in adult populations is rapidly increasing The defining clinical component is insulin loss which occurs because of sustained inflammation in the islets At present there is no means to prevent or reverse insulin loss A major inflammatory pathway in T D ...

Abstract A major shortfall in clinical care for diabetes is a rapid and accurate screen for progression to disease Current criteria involve HLA haplotype and the presence of auto antibodies AA Genome wide associated studies GWAS revealed only immune associated genes including HLA as T D predictors The ability to differentiate from other diseases was very limited Pre type diabetes p T ...

This is a Phase I STTR to investigate the preclinical efficacy of a novel immunomodulator DR MOG in a clinically relevant thromboembolic stroke model in mice We have previously shown that T cells are activated after stroke infiltrate brain and exacerbate ischemic brain damage Strategies that reduce T cell activation and brain tissue infiltration have been investigated as potential therapeu ...

Providing Army combat medics with meaningful experience in treatment of battlefield injuries is a particular challenge. Moulage has the potential to assist in acquiring what could otherwise be very hard-to-come-by preparatory experience for the distressing real-life emergencies medics and soldiers may encounter in the field. However, current approaches to moulage are limited in their ability to re ...

Investments by the Department of Defense (DOD) have led to the development and demonstration of electronic textiles capable of transforming traditional textile systems into wearable power and data systems. The Defense Health Agency (DHA) has identified an opportunity to leverage advancements in smart garment systems for military personnel to aid in the prediction in performance declines and healt ...

Cornerstone Research Group (CRG) and the University of Texas (UT) will team to develop a fast and accurate automated analysis program for USV scoring. This automated tool will enable greater research efficiency and throughput allowing greater strides in developing treatments for post-traumatic stress disorder through rodent-based research. Building off prior work by UT on a first generation auto-s ...