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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Discovery of alpha4beta2 Nicotinic Receptor Antagonists as Alcohol Abuse Medications
SBC: ASSUAGE PHARMACEUTICALS, INC. Topic: NIAAAPROJECT SUMMARY Alcohol addiction and disorders associated to excessive alcohol use are a serious public health problem in the United States and in other parts of the world Current pharmacotherapies for the treatment of these disorders show limited efficacy Preclinical and clinical findings point to nicotinic acetylcholine receptors nAChRs as an alternative promising target for the developmen ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Cancer Imaging and Therapy Platform
SBC: BIOINVISION INC Topic: 102Summary We will create a preclinical quantitative Cancer Imaging and Therapy Platform CITP which will allow one to study cancer biology and optimize pipelines of technologies imaging agents imaging methods targeted nano therapeutics tumor models etc especially for metastatic and invasive cancers Today primary tumor mass es are clinically controlled with surgical drug and radiatio ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Product Development of Intensity Modulation for Bolus Electron Conformal Therapy
SBC: Decimal, LLC Topic: 102Project Summary Abstract Electron beam therapy EBT using MeV beams provides effective radiation treatment for superficial cancers depthandlt cm As many as of radiotherapy patients in USA annually are eligible for electron therapy for some portion of their treatment making it the second most used external beam modality As many as of these electron patients ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Identifying activators of interferon regulatory factors for neuroprotection
SBC: Neuralexo, LLC Topic: 106Abstract Stroke is a leading cause of morbidity and mortality in the United States However less than of patients are eligible for the current approved interventions of tissue plasminogen activator or thrombectomy We seek to develop new therapeutics to reduce the extent of damage and functional impairment resulting from ischemic injury to the brain an area of significant unmet medical need ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Distance Filtering System for Retinal Implants
SBC: ADVANCED MEDICAL ELECTRONICS CORP Topic: NDESCRIPTION provided by applicant We propose to develop and evaluate the utility of a novel input camera system for retinal prosthetics that allows users to filter optical imagery based on distance from the observer We call this andquot depth filteringandquot which can be accomplished with a depth sensing stereoscopic camera system Retinal prostheses can restore partial vision to people bli ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Directed Chemotherapy Delivery for Leptomeningeal Metastases
SBC: Minnetronix Medical, Inc. Topic: 102DESCRIPTION provided by applicant Directed Chemotherapy Delivery for Leptomeningeal Metastases PI Lad Shivanand and McCabe Aaron Project Summary Leptomeningeal Metastases LM is a condition in which cells from a primary solid or hematological tumor metastasize invade the subarachnoid space and spread throughout the cerebrospinal fluid CSF resulting in seeding of the leptomeninges along ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Enhancing Care of the Aged and Dying in Prisons
SBC: KLEIN BUENDEL, INC. Topic: NIAThe United States has the highest rate of incarceration in the world There are over state and federal prisons housing over million prisoners in the United States The demographics of the prison population are shifting Longer sentences and constrained options for early release compound this trend The older adult segment of prison populations has more than tripled since The health ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Cell Therapy for the Treatment of Acute Respiratory Distress Syndrome
SBC: ATHERSYS, INC. Topic: NIAAADESCRIPTION provided by applicant This is a resubmission of a Phase I Phase II Fast Track application for the clinical use of MultiStem in patients with acute respiratory distress syndrome ARDS ARDS is defined as acute onset hypoxemia bilateral radiographic pulmonary infiltrates and lack of atrial pressure hypertension A novel and exiting possibility is the use of cells as part of the ther ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Simple, low cost assay for detection of HIV-1 antiretroviral resistance in resource-limited settings
SBC: Discidium Biosciences, LLC Topic: NIAIDAntiretroviral therapy has become a reality in resource limited settings thanks to entities such as PEFAR and the Global Fund However contrary to the therapeutic choice flexibility in developed countries all patients go on reverse transcriptase inhibitor RTI based first line regimens with more expensive protease and integrase inhibitor based regimens being reserved as second line therapy for ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
HELical Biodegradable Photochemical(HELP)Stents for AVF Maturation
SBC: Inovasc, LLC Topic: 300ABSTRACT Although arteriovenous fistulae AVFs are the preferred mode of dialysis vascular access over fail to mature in that they do not develop an adequate blood flow or diameter to support hemodialysis This results in a very significant clinical morbidity and economic cost At a pathogenetic level AVF maturation failure is due to a small vessels b bad non laminar hemodynamic pr ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health