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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Marrow-Derived Stem Cells for Coronary Artery Ischemia

    SBC: Arteriocyte, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Cardiovascular disease is the leading cause of morbidity and mortality in the United States, accounting for approximately 1 million deaths per year. The objective of the Phase I pre-clinical studies outlined in this fasttrack STTR proposal is to validate the proposed methods of isolation, characterization, and administration of preferred progenitor cell prepar ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Audiometric Earphone- Phase 1

    SBC: AUDIOLOGY, INC            Topic: N/A

    DESCRIPTION (provided by applicant): This project seeks to develop an earphone for diagnostic audiometry with features that will significantly increase the efficiency and decrease the cost of routine hearing testing. The most-often used earphones emply a supra-aural design that has several undesirable characteristics, including 1) an "occlusion effect", an artificial increase in sensitivity to bon ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Optimal Hydrophobicity of Lipoid Gene Delivery Agents

    SBC: AVANTI POLAR LIPIDS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Cationic lipid-like compounds are commonly used in vitro and in vivo to deliver DNA to cells for the purposes of expressing exogenous genes. A number of clinical trials have indicated the promise of these agents for gene therapy, however lipid-based delivery remains less effective than the alternative viral vectors. Nevertheless, vast improvements have been mad ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Cord Blood: Treatment for Acute Myocardial Infarction

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Transplantation of human umbilical cord stem cells (hUCBC) has been shown to be effective in limiting infarct size and in the preservation of left ventricular function and anatomy in a rat model. These effects have been present in studies both utilizing and not utilizing immunosuppression. Whether immunosuppression will be required in a large animal model is un ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Hemorrhagic Brain Injury Repair with Human Cord Blood

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Human umbilical cord blood (hUCB) is a rich source of stem cells that exhibit multipotent properties. Previous studies have shown that hUCB cells can differentiate into neural cells under the appropriate environment conditions. SANERON CCEL, Inc. is focusing on the use of hUCB as a therapeutic approach for treating a variety of neurological disorders. In this P ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. MRI Quantification of Postinfarct Myocardial Viability

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop a novel method for MRI quantification of postinfarct myocardial viability. Ultimately, the commercial embodiment of this method will be a software package that will convert a set of 2D cardiac MRI images to a 3D Myocardial Viability Map (MV) with a voxel-by-voxel resolution. In human clinical use, the package woul ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Utility of a Novel Anthracycline Analog in Psoriasis

    SBC: GEM Pharmaceuticals            Topic: N/A

    DESCRIPTION (provided by applicant): Psoriasis is a common immune-mediated disease that affects approximately 2% of the US and European populations and significantly impacts the quality of life. T cells are recognized as primary mediators of the disease and new generation therapies aimed at eliminating reactive T cells or interfering with the immunologic cascade caused by their activation have bee ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Alkoxylamine nucleosides for sequencing by synthesis

    SBC: Genomechanix, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I STTR proposal seeks funding to transfer technology from the Foundation for Applied Molecular Evolution (nonprofit) to GenoMechanix (for-profit) relating to a strategy for doing "sequencing by synthesis". This strategy involves the incorporation, in a template-directed polymerization step, of a nucleoside triphosphate having its 3'-hydroxyl group ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Internet Savvy Caregiver: Dementia Training and Planner

    SBC: HEALTHCARE INTERACTIVE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of the Internet-Based Savvy Caregiver (IBSC) program is to develop and bring to market an Internet-based psycho-educational program designed to provide persons caring for relatives who have dementing disorders the knowledge, skills, and outlook they need to undertake and succeed in the caregiving role they have assumed. The IBSC program is comp ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Chitosan hemostatic device for laparoscopic applications

    SBC: HemCon Medical Technologies Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Intraoperative bleeding can be a serious problem in parenchymal organ surgery and is generally difficult to manage during laparoscopic procedures. Our long-term goal is to develop a novel internal chitosan hemostatic device that can be deployed laparoscopically to control severe bleeding. External chitosan based hemostatic dressings have been applied success ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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