Award Data

Researchers are identifying new biomarkers to help monitor cognition and stress in the human body and enhance human performance.Traditional biomarkers like heart rate, temperature, oxygen partial pressure, blood glucose, electrolyte concentration, and others have beencorrelated with cognition and stress states. However, the correlation is indirect. Molecular biomarkers with stronger and more speci ...

The consequence of physical and mental degraded performance is of critical importance not only to the Department of Defense (DoD) missions and sports persons, but also to the general population as well. Sweat is an information abundant medium that contains biomarkers that show relation to human cognitive levels. However, obtaining days of continuous sampling of sweat from the same dermal spot has ...

Stem cell apoptosis occurs when the interaction between the host brain extracellular matrix (ECM) and human induced pluripotent stem cell (iPSC) derived neural stem cell (NSCs) are directly injected into the injured brain regions. Establishment of a connection between ECM and iPSC/NSC could increase cell viability, differentiation, and promote functional recovery of the injured tissue. The critica ...

The ultimate goal of this research is to develop a realistic, immersive 3-D environment for training en route care personnel in primary/secondary assessment, patient stabilization, patient placement, and mission management. EVAC Sim will provide medic rehearsal opportunities for evacuation patient care scenarios. The simulation will help trainees understand resources available in aeromedical aircr ...

A joint can exit its socket when it is exposed to an unhealthy level of force or rotation, causing a large amount of pain and loss of functionality in the limb. Joint dislocation can easily be diagnosed by a physical examination: palpitation of the affected joint will usually cause pain and tenderness in the patient, and the dislocated head of the bone can be felt out of its usual position in the ...

The objective of this proposal is to demonstrate the feasibility of producing molded polyurethane viscoelastic foam ear seals with an integral skin, that we call Contoured Foam Pads (CFPs). These CFPs will have a surface profile that has targeted conformability around obstacles that results in an improved acoustic seal around eyeglasses from the military Approved Protective Eyewear List (APEL) and ...

The published data has demonstrated that the currently available resuscitation fluids have detrimental effects on trauma outcomes.By addressing these deficiencies it is expected that the outcomes will improve. The crystalloid based resuscitation fluid in development by GanD Inc. has been designed to address all of the shortcomings of the currently available solutions.The solution, GND-001, is a cr ...

Currently, deployed medics are required to transport, maintain and be resupplied with liquid-based medications and materials that are heavy, expensive to transport, perishable and may require refrigeration.Many medications and materials are or will be available in concentrated or dehydrated formularies that require sterile water for injection (SWFI) to rehydrate for immediate use, such as Lactated ...

Approximately 70% of sentinel events in medical care are related to communication mishaps, and despite regular and frequent occurrence, an even higher percentage (80%) of severe medical errors are related to miscommunication during handoffs (i.e., the transferring of information, responsibility, and authority for patient care from one provider to another). The TiER1 team proposes to address challe ...

Traumatic brain injury (TBI) often occurs when a sudden trauma or head injury disrupts the function of the brain. Common causes of TBI include damage caused by explosive devices, falls and vehicle or motorcycle accidents. Sepsis is the result of a massive immune response to bacterial infection that gets into the blood. Sepsis often leads to organ failure or injury, and has always been a significan ...