Award Data

Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...

This project aims to make Laser Powder Bed Fusion (LPBF) additive manufacturing a practical tool for supply chain management for the Defense Logistics Agency.The key step is developing process standardization to make LBPF quality vendor independent. This project will seek to demonstrate the use of a promising high speed melt pool monitoring device as a practical means to establish such process sta ...

Made In Space, Inc. (MIS) and Siemens PLM Software propose an integrated Automated Processing. Monitoring, Control and Remediation System (Aul) to provide a process monitoring and control capability. Made In Space, Inc. leads the effort based on integrating Made In Space, Inc., proven inspection sensors systems with a Digital Thread for Additive Manufacturing (DTAM) system, co-developed by Siemens ...

Universal Technology Corporation (UTC) has teamed with the University of Dayton Research Institute (UDRI), Stratonics, and Macy Consulting to demonstrate not only the transitionability into commercial systems, but also to develop the data analytics and monitoring and control requirements to extract the full value fromseveral sensors, including the Stratonics ThermaViz, acoustic and profilometry se ...

Though vast improvements have been made in various protein expression platforms, limitations arise in the implementation of current purification methods. Traditional chromatographic methods are time intensive, carry heavy material costs, and are difficult to scale - reducing the benefits achieved in protein expression. Affinity-binding methods are promising for scale-up and swiftness of purificati ...

Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...

Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

A prefilled auto-injector device for storing a beneficial agent in a dry and stable format alongside a diluent, and automatically delivering the beneficial agent to a patient after reconstitution. The device comprises an automatic needle insertion mechanism and automatic needle retraction mechanism and is safe and disabled after use. The primary drug container of the auto-injector is made from ...

The published data has demonstrated that the currently available resuscitation fluids have detrimental effects on trauma outcomes.By addressing these deficiencies it is expected that the outcomes will improve. The crystalloid based resuscitation fluid in development by GanD Inc. has been designed to address all of the shortcomings of the currently available solutions.The solution, GND-001, is a cr ...