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DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...

DESCRIPTION provided by applicant Dramatic advances in the development of biomedical ontologies hold the promise of a deeper and clearer understanding of the molecular and genetic aspects that affect human health Biomedical data and knowledge stored in ontologies and databases have the potential to empower researchers in the life sciences to access and find conclusive evidence that can be translat ...

DESCRIPTION provided by applicant Evaluation of dental tobacco cessation tool in practice based research network This Phase II project will finish development and evaluate QuitAdvisorDDS as a tool for dental providers to advise patients on tobacco cessation The University of Kentucky will evaluate the effectiveness of QuitAdvisorDDS in increasing quit attempts in tobacco using patients The ev ...

DESCRIPTION In this SBIR Phase II PicoCal will develop a high throughput apparatus to measure changes in cell adhesion at the level of individual receptor ligand interactions in real time This tool finds critical applications in research and drug development and would allow researchers to study and manipulate adhesion by bioactive compounds to promote or inhibit physiological processes There is a ...

DESCRIPTION provided by applicant This application andquot Imaging Software of Functional Connectivity MRI for Alzheimerandapos s Diseaseandquot is written in response to PA andquot Lab to Marketplace Tools for Brain and Behavioral Research SBIR R R andquot Alzheimerandapos s disease AD is the most common form of dementia However developing drugs that effectively slow or alter the course of Alzhei ...

DESCRIPTION provided by applicant My Coverage Plan Inc MCP proposes to use our newly patented technology to create a commercially viable and nationally replicable suite of software and services for health care providers and other social service agencies that reduces avoidable health disparities and increases provider reimbursements The MCP health IT solution will help providers proactively ...

DESCRIPTION provided by applicant Noroviruses are a group of enteropathogenic viruses belonging to the taxonomic family Caliciviridae which causes approximately of epidemic non bacterial outbreaks of gastroenteritis around the world and may be responsible for of all foodborne outbreaks of gastroenteritis in the US In developing countries according to a estimate by CDC researchers up to children le ...

DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

The Return on Investment Tool for Effective Medical Training (RITE-MT) tool aims to substantially improve the decision making process of training system requirements and acquisition professionals by objectively quantifying training system Return On Training Investment (ROTI) based on lifecycle cost, schedule and performance impacts. RITE-MT uses a training needs-based approach to ROTI which incorp ...

Concern has been raised over the prevalence of behavioral health disorders in military personnel returning from deployment to the Middle East. While not appearing as an overt physical injury, disruptions of a psychological nature are often as debilitating, and there is an increasing need for support tools. Such tools should allow for standardized tracking, monitoring, and mitigation of anger and ...