Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD Research Corporation            Topic: CBD10103

    Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  2. A Novel, Aerodynamics-augmented Continuous Ionization System for Electrostatic Collection of Bioaerosols

    SBC: CFD Research Corporation            Topic: CBD12107

    Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  3. A rapid and high-throughput microfluidic stem cell analyzer

    SBC: CFD Research Corporation            Topic: OSD11H14

    Current methods to discern the differentiation state of stem cells are time-consuming, labor-intensive, costly, invasive, and consequently, ill-suited for clinical applications. To overcome these limitations, we propose to develop a microfluidic stem cell analyzer for accurate, non-invasive identification of the cell differentiation state in conjunction with automated cell sorting at high-throughp ...

    SBIR Phase II 2013 Department of DefenseDefense Health Program
  4. AC Impedance Sensor for Collective Protection Filter Residual Life Indicator

    SBC: Guild Associates, Inc.            Topic: CBD10106

    Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  5. An automated, high throughput, resin-free device for large scale protein purification

    SBC: CFD Research Corporation            Topic: CBD12102

    Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  6. ARCH Technology for a Simple, Resilient, and Cost-Effective Auto- Injector

    SBC: AKTIVAX, INC.            Topic: CBD13106

    A prefilled auto-injector device for storing a beneficial agent in a dry and stable format alongside a diluent, and automatically delivering the beneficial agent to a patient after reconstitution. The device comprises an automatic needle insertion mechanism and automatic needle retraction mechanism and is safe and disabled after use. The primary drug container of the auto-injector is made from ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  7. CBRN Sensor and Sensor Netting Algorithms

    SBC: Numerica Corporation            Topic: CBD09110

    Coordination and merging of multiple distributed sensors over a communications network can substantially improve estimates of the type and severity of potential hazards for command and control (C2) decision makers. These sensors include long range instruments such as radar, infrared (IR), electro-optical, and long wave hyper spectral; short range instruments such as Raman spectrometers; and a wid ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  8. CBRN Sensor and Sensor Netting Algorithms

    SBC: Torch Technologies, Inc.            Topic: CBD09110

    information) During Phase I the Torch Technologies developed, demonstrated, and assessed the feasibility of an innovative, real-time multi-layered CW sensor data fusion network capability supporting advanced standoff detection and early warning against CB threats. Torch merged two significant technologies that we developed for the Department of Defense: 1) the ACRES CW multi-sensor data fusion t ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  9. Chronological Sweat Sensor Patch for Real-Time Human Molecular Biomarker Monitoring

    SBC: TDA Research, Inc.            Topic: DHA18003

    Sweat contains biomarkers that give an indication of human cognitive levels. In this SBIR project TDA Research is developing a modular sweat sensor patch that has the capability to not only carry out real-time monitoring of select biomarkers, but also to collect multiple precisely time stamped chronological samples (50-150 Ls each) for off-line analysis in laboratory assays.In Phase I, we demonstr ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  10. Complex Crystalloid Resuscitative Fluid

    SBC: GanD Inc            Topic: DHA172009

    Problem: Currently available resuscitation fluids have been shown to induce detrimental effects on trauma outcomes.Objective: The objective of this proposal is to use the data from the successful Phase 1 studies to guide the continued development and testing of the novel resuscitation fluid (GND-001), which has been designed to address the deficiencies of current resuscitation fluids.Proposed work ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
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