You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A single dose long-acting non-addictive polymer conjugate formulation of buprenorphine that provides immediate and prolonged analgesia for post-operative pain

    SBC: SERINA THERAPEUTICS INC            Topic: NINDS

    PAProject Summary Abstract SERis a long acting polymer pro drug of buprenorphine that is being developed to treat postoperative pain following major surgeries such as bunionectomyabdominoplastythoracotomy and knee and hip surgerySERhas no biological activity by itselfbut when administered in vivo by subcutaneous injection it enters the vascular compartment where a plasma esterasebutyrylcholinester ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A SAFE AND COMPACT NEONATE TO ADULT NEUROIMAGING MRI SYSTEM

    SBC: ADVANCED IMAGING RESEARCH, INC.            Topic: 101

    NIH SBIR PAw o Clinical Trials A Safe and Compact Neonate to Adult Neuroimaging MRI System The intriguing human brain is the most imaged end organ non invasivelywithout ionizing radiation using magnetic resonance imagingMRIHigh spatial resolution brain MRI is an established diagnostic tool to assess injury mechanisms affecting newborn growth and the adult human connectomeTo predict neurodevelopmen ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Antithrombotic Protein C Activator for Hemodialysis

    SBC: Aronora, Inc            Topic: y

    Project Summary Although potent antithrombotic drugs are availableall inadvertently target vital hemostatic mechanismsresulting in dose limiting hemorrhagic toxicity that restricts their useDue to a lack of safe thromboprophylaxisthrombotic thromboembolic blood vessel occlusions and vascular device failures remain among the leading causes of death and severe chronic disability in the U SConsequent ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Effect of Repeated Administration of G-CSF on Hot Flashes and Other Vasomotor Symptoms of Menopause

    SBC: MENOGENIX, INC.            Topic: NIA

    One of the most common and distressing symptoms of menopause are hot flashesHot flashes and related symptoms represent a significant unmetworldwidehealthcare neednot only in women after surgical or natural menopausebut also in breast and prostate cancer patients undergoing hormone suppression or ablationHot flashes occur inof women undergoing natural menopause and approximatelymillion individuals ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Stem Cells for Treating Acute Stroke

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: 999

    ABSTRACT SUMMARY In previous studies we identified novel non hematopoietic umbilical cord blood stem cellsnhUCBSCsthat could be expanded to high passages and exhibit restorative properties following ischemic brain injury repairWe found that the high passaged cells were equivalentif not even betterthan the low passaged nh UCBSCsThis finding suggests that these cells can serve as a source of highly ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Human on a chip system to investigate genetic risk factors in Alzheimer's disease

    SBC: Hesperos, Inc.            Topic: NIA

    Project Summary AbstractHesperos will construct and test microscale multi organ systems with recirculating blood and cerebral spinal fluid surrogates that will give insights to the responses of various Alzheimer s phenotypes to drugs as well as the influence of peripheral effects on AD progressionspecifically ApoE variantsWe seek to leverage DrMorgan s research on Alzheimer s and aging combine it ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Function-based Variant Assessment of Epilepsome Genes to Increase Diagnostic Yield

    SBC: NEMAMETRIX, INC            Topic: 101

    epilepsome phaseJanGoogle Docs Technical Summary Epilepsy is a significant health problem affectingof the human populationGenome wide DNA sequencingwhich is now being adopted in clinical practicehas led to the identification of an increasing number of variants a in epilepsy associated genesHoweverclinical interpretation of the new variants is challengingSome of the variants are known to be either ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. rAAV5-hCNGB3 Gene Therapy for Achromatopsia: Safety and Efficacy in a Dog Model

    SBC: APPLIED GENETIC TECHNOLOGIES CORPORATION            Topic: N

    DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. ADVANCED NEXT GEENRATION RADIO FREQUENCY COILS FOR MAGNETIC RESONANCE IMAGING

    SBC: ADVANCED IMAGING RESEARCH, INC.            Topic: 101

    Magnetic resonance imagingMRIis a safenon ionizing diagnostic toolThe overall goal of this project is to arrive very close to the ultimate intrinsic signal to noise ratioUISNRfor a given MRI magnet field strength by combining innovations in very advanced transceiver technologyIn Phase Ia high performance head RF coil receiver array will be prototyped and SNR performance compared to an existing com ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Bioinformatic Tools for Interpretation of Glycan Array Data

    SBC: Z Biotech, LLC            Topic: 400

    Project SummaryAbstract There is an urgent need of bioinformatic tools for mining glycan array data in order to accurately and statistically study the interactions between cell surface glycans and glycan binding proteinsWe propose here to develop a software and hardware integrated system for the interpretation of glycan array dataThe problem with existing glycan array data mining tools is that the ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government