Award Data

DESCRIPTION (provided by applicant): This proposed project will create an ultra-low power, digital wireless transceiver as an integrated circuit (IC) which will enable communication between hearing aids worn in the left and right ears in a binaural system. Wireless synchronization between the digital signal processors of two hearing instruments is a new technology for next generation hearing inst ...

DESCRIPTION (provided by applicant): The objective of this project is to develop a hearing aid and wireless companion microphone system based on new, highly-innovative, very low-power ultra-wideband impulse radio technology. The phase I program successfull y established the feasibility of fully integrating an ultra-wideband (UWB) impulse radio transceiver and antenna system inside a behind-the-ear ...

DESCRIPTION (provided by applicant): Skilled Service Personnel (SSP) support emergency response organizations during an emergency incident, and include laborers, operating engineers, carpenters, ironworkers, sanitation workers and utility workers. SSP called to an emergency incident rarely have recent detailed training on the chemical, biological, radiological, nuclear and/or explosives (CBRN ...

DESCRIPTION (provided by applicant): BioInVision, Inc. and Case Western Reserve University researchers will develop a cryo-imaging system for 3D imaging of mice. It will serve very many applications in biological research and the biotechnology industry, in cluding mouse anatomical phenotyping, drug delivery, imaging agents, metastastic cancer, pathogen/immune system response, and stem cells/regene ...

DESCRIPTION (provided by applicant): We propose to develop an interactive Internet-based program (WeBREATHe: Web-Based Respiratory Education About Tobacco and Health) to train pediatric respiratory therapists and nurses to provide brief, hospital-based tob acco cessation interventions to parents of hospitalized pediatric patients. During Phase I, we designed and evaluated a prototype program, base ...

DESCRIPTION (provided by applicant): The focus of this proposal is the development of a novel in-vivo imaging device (Molecular Breast Imaging system) that incorporates a clinical validation experiment and a limited pilot and a clinical feasibility evaluation for pre-clinical and clinical studies. Our primary intent is to facilitate the proof of feasibility of this novel imaging device for early ...

DESCRIPTION (provided by applicant): Sequencing during synthesis (SdS) is an architecture for massively parallel DNA sequencing that has the strong potential of lowering the cost of sequencing enough to allow individuals access to their own genetic heritag e as a way of personalizing their medical care. Thus far, however, higher-throughput next-generation sequencing systems are relatively expensiv ...

DESCRIPTION (provided by applicant): Chronic lung disease remains America's third largest cause of death. Adult respiratory distress syndrome (ARDS) alone afflicts approximately 150,000 patients every year with a mortality rate between 30-70%. Current ther apy for respiratory failure includes mechanical ventilation and extracorporeal membrane oxygenation (ECMO). Mechanical ventilation is effective ...

DESCRIPTION (provided by applicant): The overall goal of this project is to further develop novel bisphosphonate conjugate MBC-11 as treatment for tumor-induced bone diseases such as those associated with multiple myeloma. MBC-11 is the anhydride formed be tween arabinocytidine (AraC)-5'-phosphate and etidronate and is the lead product of our proprietary technology which employs conjugates of know ...

DESCRIPTION (provided by applicant): Federal and state laws require that young children with disabilities or who are at risk for developing disabilities be provided with Early Intervention services according to their developmental needs. But currently ther e is a critical shortage of skilled EI providers. The primary reason for this shortage is a lack of educational and training programs. Except f ...