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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A cost-effective bioreactor to advance functional tissue engineering of cartilage

    SBC: Apex Biomedical Company, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the leading cause of chronic disability in the United States. A clinical goal in the treatment and prevention of OA is to develop replacement cartilage using tissue engineering (TE) technologies. Although TE cartilage presently lacks the mechanical stability of native cartilage, studies have demonstrated that mechanical stability can be e ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Additive Manufacture of Refractory Metal Propulsion Components

    SBC: GEOPLASMA LLC            Topic: T9

    Niobium alloy (C-103) reaction control system (RCS) chambers have been used on numerous NASA programs. However at elevated temperatures, the strength of C-103 decreases significantly. Higher strength niobium alloys have been developed, but these alloys lack the formability of C-103. Recently, Additive Manufacture (AM) of niobium and C-103 has been demonstrated using powder bed electron beam me ...

    STTR Phase I 2018 National Aeronautics and Space Administration
  4. A Device to Quantify Sweat of Single Sweat Glands to Diagnose Neuropathy

    SBC: Neuro Devices, Inc.            Topic: 107

    DESCRIPTION provided by applicant We devised a new generation highly sensitivity method to diagnosis peripheral neuropathy early when the probability for reversal is greatest Cancer chemotherapy and diabetes are the most common causes of neuropathy in the USA Both cause decreased sweating abnormal circulation peripheral numbness pain and weakness If diagnosed early both are potentially ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. A 3D Printed Resorbable Antimicrobial Envelope to Prevent Infection of Implanted Cardiac Devices

    SBC: N8 MEDICAL INC            Topic: NHLBI

    ABSTRACT Infection is a serious and potentially fatal complication of surgery to deliver cardiovascular implantable electronic devicesCIEDsi epacemakers and implantable cardioverter defibrillatorsUntreated device related infection is associated with mortality rates as high asCurrentlyonly one antibiotic impregnated mesh has been FDA approved for placement in surgical incisions to reduce infections ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Advanced Simulation Framework for Design and Analysis of Space Propulsion Systems

    SBC: STREAMLINE NUMERICS, INC.            Topic: T901

    The innovation proposed here is a high-performance, high-fidelity framework in the computational fluid dynamics (CFD) code called Loci-STREAM to enable accurate, fast and robust simulations of unsteady multiphase flows such as combustion involving liquid-gas phases in liquid rocket injectors and solid-gas phases in solid rocket motors, and cryogenic cavitation in delivery systems of liquid rocket ...

    STTR Phase II 2010 National Aeronautics and Space Administration
  7. Advanced Unsteady Turbulent Combustion Simulation Capability for Space Propulsion Systems

    SBC: STREAMLINE NUMERICS, INC.            Topic: T901

    The innovation proposed here is a high performance, high fidelity simulation capability to enable accurate, fast and robust simulation of unsteady turbulent, reacting flows involving cryogenic propellants (such as LOX/LH2 and LOX/LCH4). The key features of this proposed capability are: (a) Hybrid RANS-LES (HRLES) methodology, and (b) flamelet modeling for turbulent combustion incorporated in a pr ...

    STTR Phase I 2010 National Aeronautics and Space Administration
  8. A Home Exercise Program (DVD) for Women with Infants and Young Children

    SBC: KLEIN BUENDEL, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): Becoming a mother is a significant transition in a woman's life. This transition can precipitate major changes in health behaviors, like physical activity. Once a woman has a child she is much less likely to participate in regular, moderate to vigorous physical activity compared to women without children. Thus, new mothers are at risk for future weight gain and ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  9. AHTP-comet: development of an automated, high throughput comet assay system

    SBC: ENGINEERING RESOURCES GROUP INC            Topic: NIEHS

    PROJECT SUMMARY Genomic instabilityinduced by DNA damageand partly mitigated by DNA repair and antioxidantsplays a critical role in the pathogenesis of many major human diseasessuch as neurodegenerationcancer and cardiovascular diseasetogether with agingThere is a critical need for automated assays that can perform these assessmentsand bring them into greater routine usewhich will help advance our ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Air Vehicle Gust Response analysis for Conceptual Design

    SBC: RESEARCH IN FLIGHT LLC            Topic: T15

    Research in Flight (RIF) and Auburn University are offering the development of an advanced, robust tool and methodology that allows the simulation and modeling of gust and wake vortex encounters for Distributed Electric Propulsion (DEP) enabled Urban Air Mobility (UAM) vehicle concepts. DEP enabled UAM concepts offer the potential for large performance improvements by exploiting favorable synergie ...

    STTR Phase I 2019 National Aeronautics and Space Administration
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