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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10103

    Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  2. Microfluidic High-throughput Platform for Determining of Kinetic Constants of Enzyme Variants

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10107

    Molecular biology techniques allow generating combinatorial libraries of large number of enzyme variants. However, there is currently no technology available for screening the enzyme libraries for identifying variants with improved activity for the substrate. We propose to develop a novel, microfluidic, high-throughput platform for determining kinetic constants of enzyme variants and identifying v ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  3. Novel MicroPower Source for Insect Based Sensor and Communication Platforms

    SBC: CFD RESEARCH CORPORATION            Topic: CBD09105

    Our objective is to develop a novel micropower source to be integrated with a microsensor, and communication chip on an insect, delivering a state-of-the-art unmanned chemical detection device. The biological fuel cell (Bio-FC) power source will leverage ongoing research at CFDRC and provide a compact/lightweight power supply for mounting on numerous types of insects and producing necessary power ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  4. AC Impedance Sensor for Collective Protection Filter Residual Life Indicator

    SBC: GUILD ASSOCIATES INC            Topic: CBD10106

    Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  5. CBRN Sensor and Sensor Netting Algorithms

    SBC: NUMERICA CORPORATION            Topic: CBD09110

    Coordination and merging of multiple distributed sensors over a communications network can substantially improve estimates of the type and severity of potential hazards for command and control (C2) decision makers. These sensors include long range instruments such as radar, infrared (IR), electro-optical, and long wave hyper spectral; short range instruments such as Raman spectrometers; and a wid ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  6. Bio-MEMs Agile Sensor Platforms and Communication Networks

    SBC: OpCoast LLC            Topic: CBD09105

    This effort continues the development of "OrthopterNets" -- a novel approach applying mobile ad hoc network (MANET) communications networks for the transfer of intelligent information via insect calls (e.g., cricket calls). Insects will be equipped with embedded MEMS transceivers that pick up modulated calling sounds from nearby insects. Once the information in a call is extracted by the transceiv ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  7. CBRN Sensor and Sensor Netting Algorithms

    SBC: Torch Technologies, Inc.            Topic: CBD09110

    information) During Phase I the Torch Technologies developed, demonstrated, and assessed the feasibility of an innovative, real-time multi-layered CW sensor data fusion network capability supporting advanced standoff detection and early warning against CB threats. Torch merged two significant technologies that we developed for the Department of Defense: 1) the ACRES CW multi-sensor data fusion t ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  8. An automated, high throughput, resin-free device for large scale protein purification

    SBC: CFD RESEARCH CORPORATION            Topic: CBD12102

    Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  9. A Novel, Aerodynamics-augmented Continuous Ionization System for Electrostatic Collection of Bioaerosols

    SBC: CFD RESEARCH CORPORATION            Topic: CBD12107

    Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  10. ARCH Technology for a Simple, Resilient, and Cost-Effective Auto- Injector

    SBC: AKTIVAX, INC.            Topic: CBD13106

    A prefilled auto-injector device for storing a beneficial agent in a dry and stable format alongside a diluent, and automatically delivering the beneficial agent to a patient after reconstitution. The device comprises an automatic needle insertion mechanism and automatic needle retraction mechanism and is safe and disabled after use. The primary drug container of the auto-injector is made from ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
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