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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Biological Activity Assay and Bioanalytical Test Method Development for a Silk-Derived Protein (SDP) Eye Drop Product

    SBC: SILK TECHNOLOGIES, LTD.            Topic: NonDoD

    The company has developed a silk-derived protein (SDP) for use as a novel ophthalmic formulation excipient that will help to treat the ocular injuries and dry eye pathology that affects over 40 million Americans annually and hundreds of millions of people worldwide. The SDP excipient is designed to enhance tear formulation comfort, longevity, and overall ocular health. This proposal builds on the ...

    SBIR Phase II 2019 Department of DefenseDefense Health Agency
  2. Extended Release of Pyridostigmine Bromide for Effectively Combating Nerve Agent Exposure

    SBC: INNOSENSE CORPORATION            Topic: CBD181004

    Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigmine bromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it acts as a “temporary” inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitig ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Dual Formulation of Atropine/Scopolamine with Enhanced Stability

    SBC: CMC PHARMACEUTICALS INC            Topic: CBD181005

    CMC Pharmaceuticals, Inc. (Cleveland, OH) is proposing developing a stable, combination product of two small molecule drug candidates as a counter measure to chemical warfare nerve agents (NA). The combination product is expected to exploit complementary pharmacological profiles for optimal muscarinic receptor blockade and anticholinergic activity within the peripheral and central nervous system. ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  4. Sequential Phase II Proposal for Smartphone Application for Mask Sizing and Projecting Quantitative Fit

    SBC: Physical Optics Corporation            Topic: CBD181006

    To address the Chemical and Biological Defense (CBD) need for a field-portable mass spectrometer for small molecule drugs in clinical samples, Physical Optics Corporation (POC) proposes to develop a new FiEldable DRug Mass Analysis (FERMA) system based on a combination of portable mass spectrometry technology with laser desorption/ionization for use with aqueous clinical samples. The FERMA system ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  5. Field Portable Mass Spectrometry for Small Molecule Drugs in Clinical Samples

    SBC: SPECTRAL ENERGIES LLC            Topic: CBD181006

    We propose a novel two-dimensional mass spectrometry (2D-MS) technique based on ion trap arrays to identify illicit and designer drugs. This approach will give an unprecedented multiplex advantage for miniature mass spectrometry, allowing novice field technicians to rapidly identify drugs affecting the central nervous system based on both the m/z ratio and fragmentation pattern of an ion. Towards ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  6. Photoacoustic Gasses Optical Detector and Analyzer

    SBC: Physical Optics Corporation            Topic: CBD171004

    To address the CBD’s need for real-time analytical technology for multicomponent vapor identification and quantification, Physical Optics Corporation (POC) proposes to continue the development of a new Photoacoustic Gasses Optical Detector and Analyzer (PAGODA) autonomous, network-enabled photoacoustic spectrometer (PAS) for the correlation, analysis, and identification of measured spectra. In t ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  7. MicroLens Hyperspectral Imager for Standoff Chemical Detection

    SBC: SURFACE OPTICS CORP.            Topic: CBD171002

    A program to develop a compact, MLA-based, LWIR, full-motion-video hyperspectral imager for chemical detection is proposed. The proposed Hyperspectral Chemical Imaging Sensor (HyCIS) builds upon Surface Optics’ real-time hyperspectral imaging activities, including our 3D full-motion-video spectral imaging (FMV-SI) technology and our MIDIS hyperspectral image processor. Simultaneously sampling 16 ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  8. MicroLens Hyperspectral Imager for Standoff Chemical Detection

    SBC: SA PHOTONICS, LLC            Topic: CBD171002

    SA Photonics is please to submit the proposal for the HawkEye compact LWIR hyperspectral imaging system. HawkEye leverages SA Photonics previous visible, SWIR, and LWIR programs to result in a compact, hand held, battery operated hyperspectral imager in a low cost design approach. Furthermore, HawkEye will leverages SA Photonics expertise in warfighter body worn equipment and ground troop personal ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  9. High Bandwidth Redundant Communication Links for Small Satellites

    SBC: Innoflight, Inc.            Topic: A16079

    Innoflight will develop a high performance software-defined compact radio (SCR) with Ka and X dual band downlink capability and S Band uplink capability. The Ka / X SCR will support 300 Mbps downlink and 5 Mbps uplinks rates using advanced spectrally efficient waveforms. It will offer interoperability with standard government and commercial ground stations such as the Army RGT (Remote Ground Termi ...

    SBIR Phase II 2019 Department of DefenseDefense Health Agency
  10. Ocular Penetrating/Perforating injuries Assessment Hydrogel system (OPPAH)

    SBC: CHROMOLOGIC LLC            Topic: DHA182004

    In order to meet Defense Health Agency’s need for rapid confirmation and evaluation of open globe injuries, to allow for appropriate initial triage, evacuation, and treatments, ChromoLogic LLC (CL) proposes to develop an Ocular Penetrating/Perforating inj

    SBIR Phase I 2019 Department of DefenseDefense Health Agency
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