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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Production of High Specific Activity Lutetium-177

    SBC: ALPHAMED, INC            Topic: N/A

    DESCRIPTION (provided by applicant): A separation method will be tested and evaluated to determine the feasibility of providing no carrier added lutetium-177 (Lu-177) for use in radiotherapeutic applications. An indirect method will be used to produce Lu-177 (neutron capture followed by decay). Separation of the Lu-177 from the target material will enable us to provide carrier-free Lu-177 suita ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Novel Nanostructured Calcium Phosphate for Gene Delivery to Bone

    SBC: Angstrom Medica, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Osteoporosis is a major and growing health care problem that responds inadequately to standard pharmacologic therapy. Because of its low bone mineral density, osteoporotic bone is mechanically weak and fractures more easily than normal bone. Moreover, fracture repair is compromised in osteoporotic patients. The work described in this Phase I STTR proposal aims ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Marrow-Derived Stem Cells for Coronary Artery Ischemia

    SBC: Arteriocyte, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Cardiovascular disease is the leading cause of morbidity and mortality in the United States, accounting for approximately 1 million deaths per year. The objective of the Phase I pre-clinical studies outlined in this fasttrack STTR proposal is to validate the proposed methods of isolation, characterization, and administration of preferred progenitor cell prepar ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Audiometric Earphone- Phase 1

    SBC: AUDIOLOGY, INC            Topic: N/A

    DESCRIPTION (provided by applicant): This project seeks to develop an earphone for diagnostic audiometry with features that will significantly increase the efficiency and decrease the cost of routine hearing testing. The most-often used earphones emply a supra-aural design that has several undesirable characteristics, including 1) an "occlusion effect", an artificial increase in sensitivity to bon ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Optimal Hydrophobicity of Lipoid Gene Delivery Agents

    SBC: AVANTI POLAR LIPIDS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Cationic lipid-like compounds are commonly used in vitro and in vivo to deliver DNA to cells for the purposes of expressing exogenous genes. A number of clinical trials have indicated the promise of these agents for gene therapy, however lipid-based delivery remains less effective than the alternative viral vectors. Nevertheless, vast improvements have been mad ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Design of an Automated Psoriasis Treatment System

    SBC: Boston Array Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Up to 3 percent of populations worldwide have psoriasis. A large number of the patients with psoriasis can be treated using UV light exposure. We propose to employ a light modulating microchip based on recent Micro Electro Mechanical Systems (MEMS) technological developments to build an Automated Psoriasis Treatment System. The overall goal of Phase I a ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Cord Blood: Treatment for Acute Myocardial Infarction

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Transplantation of human umbilical cord stem cells (hUCBC) has been shown to be effective in limiting infarct size and in the preservation of left ventricular function and anatomy in a rat model. These effects have been present in studies both utilizing and not utilizing immunosuppression. Whether immunosuppression will be required in a large animal model is un ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Hemorrhagic Brain Injury Repair with Human Cord Blood

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Human umbilical cord blood (hUCB) is a rich source of stem cells that exhibit multipotent properties. Previous studies have shown that hUCB cells can differentiate into neural cells under the appropriate environment conditions. SANERON CCEL, Inc. is focusing on the use of hUCB as a therapeutic approach for treating a variety of neurological disorders. In this P ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Use of Self-Assembled Crystals in Cyanide Detection

    SBC: CHEMMOTIF, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): ChemMotif, Inc. is developing a range of sophisticated test strips that are reliable and sufficiently sensitive to be useful in public health, environmental, and homeland security applications. The objective of this proposal is the development of an improved analytical test strip for the determination of cyanide in water at or below EPA actionable levels (0. ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. MRI Quantification of Postinfarct Myocardial Viability

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop a novel method for MRI quantification of postinfarct myocardial viability. Ultimately, the commercial embodiment of this method will be a software package that will convert a set of 2D cardiac MRI images to a 3D Myocardial Viability Map (MV) with a voxel-by-voxel resolution. In human clinical use, the package woul ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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