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SBC: Z Lens LLC Topic: NEI
DESCRIPTION (provided by applicant): We are developing an accommodative - disaccommodative intraocular lens implant (ADIOL) system based on a novel concept of capturing zonular tension and transmitting it unimpeded to a dynamically position intraocular lens system. This is made possible by a zonular capture haptic (ZCH) apparatus. This apparatus lends itself equally well to several possible combin ...STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
SBC: KITWARE INC Topic: NIBIB
DESCRIPTION (provided by applicant): Validation of computing algorithms has been a challenging topic over the last few years. In fact, several international workshops in the medical imaging field started to involve the community through grand challenges . A grand challenge involves selecting driving biological/scientific problem and asking experts to submit their best results and methods to solve ...STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
SBC: VORTANT TECHNOLOGIES, LLC Topic: NIA
DESCRIPTION (provided by applicant): Freezing of Gait (FOG) effects the majority of the approximately one million individuals who have Parkinson's disease nationwide and causes a cessation of movement that patients describe as feeling as if their feet are glued to the ground . FOG most often occurs in the mature stages of Parkinson's disease and results in a loss of balance and severe falls. Thes ...STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
SBC: VIRTUAL PHANTOMS INC Topic: NIBIB
DESCRIPTION (provided by applicant): This project aims to develop a commercial software product, VirtualDoseTM, for calculating and analyzing patient radiation doses from x-ray computed tomography (CT) examinations. Despite its essential role in radiology, CT is responsible for raising the collective medical radiation dose to the American population to a level that is associated with measurable a ...STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
SBC: Quadrant Biosciences Inc. Topic: 105
Project Summary Abstract Autism spectrum disorder ASD is a continuum of neurodevelopmental characteristics that includes deficits in communication and social interaction as well as restrictive repetitive interests and behaviors ASD is an increasing public health concern with about in American children diagnosed with ASD in a fold increase in prevalence over the past years T ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: Simulated Inanimate Models LLC Topic: 103
Project SummarySimulation training is unique in its ability for repetitive practice of a wide variety of scenarios and to reflect on performance without jeopardizing a patient s safetySurgical skills simulators have been successful in bridging gaps of the current training modelhoweverthese simulators fall short of offering a complete operative experienceOperative exposure with live patients still ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
Using advanced natural language processing to facilitate documentation of meaningful use and quality payment complianceSBC: Safermed, LLC Topic: NLM
PROJECT SUMMARY The Center for Medicare and Medicaid Services Quality Payment Program is designed to motivate healthcare providers to adhere to best practices in clinical healthcare and patient safetyUnfortunatelyextracting quality measures data from the clinical record is burdensome and as suchparticipation among clinical healthcare providers is suboptimalOur aim is to develop a system to facilit ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
Use of a Designer Proline-rich antimicrobial peptide Chaperone protein inhibitor (DPC) for treating antibiotic resistant pneumoniaSBC: Arrevus, Inc. Topic: NIAID
Project SummaryInfectious disease is the third leading cause of death in the United Statesand hospital acquired infectionsHAIsin particular affectmillion patients annuallyThe most common type of HAI is pneumoniaoften caused by multi drug resistantMDRpathogens such as Staphylococcus aureusPseudomonas aeruginosaKlebsiella pneumoniaeEscherichia coliand Acinetobacter baumanniiRates of antibiotic resis ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: TRITON SYSTEMS, INC. Topic: DHA17C002
Triton Systems, Inc. proposes to develop a piezo-textile that can capture underwater explosion pressure wave patterns to ultimately establish and monitor for injury risk severity. We propose to use a state-of-the-art piezo-textile to which we will apply our own proprietary treatments.We will assess our textiles pressure detection performance and durability against a non-textile piezoelectric array ...STTR Phase I 2018 Department of DefenseDefense Health Agency
SBC: CORTICOMETRICS LLC Topic: NIA
Project Summary Normal human neuroanatomy is incredibly variableand increases with ageThis impedes the ability of neuroimaging to detect effects in neurological conditions such as Alzheimerandapos s diseaseADHuntingtonandapos s diseaseHDmultiple sclerosisMSand schizophreniaMost of the recently available state of the art quantitative imaging tools still use cross sectional methods to analyze repeat ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health