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Use of Highly Porous Polymer Beads to Remove Anti-A and Anti-B Antibodies from Plasma for TransfusionSBC: CYTOSORBENTS MEDICAL INC Topic: DHP15B001
The ready availability of universal donor plasma to rapidly treat massively bleeding hospital trauma patients and warfighters with combat casualties is a key element of current recommendations for trauma resuscitation, yet universal AB donor plasma is relSTTR Phase I 2016 Department of DefenseDefense Health Agency
SBC: Corvid Innovation LLC Topic: DHP16A001
Realistic surgical simulation requires a combination of representative tissue geometry, accurate tissue material properties and lifelike tool-tissue interaction forces. Recent advances in computational power and imaging modalities have provided the capability to represent the anatomical details required for surgical training; however, the mathematical models which govern the underlying tissue pro ...STTR Phase I 2016 Department of DefenseDefense Health Agency
SBC: CFD RESEARCH CORPORATION Topic: DHP16A001
Surgical simulations aiming to support surgeon practices and medical education have attracted enormous research effort over the last two decades. However, the physical reality, especially on simulating aggregated tissue interaction, is still unsatisfactory. In this proposed work, an open source surgery simulation framework, SoFMIS, will be utilized and enhanced with tissue interaction models to a ...STTR Phase I 2016 Department of DefenseDefense Health Agency
SBC: BIOMOJO LLC Topic: DHP16A001
BioMojo LLC and the Departments of Mathematics and Biomedical Engineering at the University of North Carolina Chapel Hill, will develop a preliminary bio mathematical model framework to represent how human tissues interact and behave at their boundaries. Tissue interaction properties (e.g. tensile, shear, friction, and so forth) of connective, epithelial, muscular, and nervous tissue including su ...STTR Phase I 2016 Department of DefenseDefense Health Agency
SBC: Tier 1 Performance Solutions, LLC Topic: DHA17B002
Approximately 70% of sentinel events in medical care are related to communication mishaps, and despite regular and frequent occurrence, an even higher percentage (80%) of severe medical errors are related to miscommunication during handoffs (i.e., the transferring of information, responsibility, and authority for patient care from one provider to another). The TiER1 team proposes to address challe ...STTR Phase I 2018 Department of DefenseDefense Health Agency
SBC: GLOBAL RESEARCH & DEVELOPMENT INC Topic: DHA17B005
This proposal is in response to the Defense Health Agency 2017 Phase I SBIR topic 17B-005.The approach is the use of a membrane oxygen pump using newly developed nano-thickness membranes with all the layers less than 1 micron total.Nanometer thickness membranes enable more oxygen output per surface area at temperatures of 300-600 C than current state-of-the -art 600-800 C membranes that are 50-300 ...STTR Phase I 2018 Department of DefenseDefense Health Agency
SBC: APTIMA INC Topic: DHA17C001
Adverse physiological events (PEs) have plagued warfighters piloting military aircraft, in particular PEs involving hypoxia and cockpit cabin decompression. Though there has been a large variety of research performed in trying to understand the problems and why theyre caused, there are inefficiencies due to the lack of standardized cross-laboratory protocols, procedures, and metrics. To address th ...STTR Phase I 2018 Department of DefenseDefense Health Agency
SBC: Ionica Sciences, Inc Topic: DHA17B004
Traumatic brain injury (TBI) often occurs when a sudden trauma or head injury disrupts the function of the brain. Common causes of TBI include damage caused by explosive devices, falls and vehicle or motorcycle accidents. Sepsis is the result of a massive immune response to bacterial infection that gets into the blood. Sepsis often leads to organ failure or injury, and has always been a significan ...STTR Phase I 2018 Department of DefenseDefense Health Agency
SBC: TRITON SYSTEMS, INC. Topic: DHA17B004
Triton Systems will develop a novel approach to field-based disease and biochemical diagnostics through innovative use of extremely low cost bioanalytical devices.The proposed platform will provide a low cost, portable, and reliable diagnostic test for on-site use in austere and resource-limited environments.The devices will be highly durable, rugged, and easy to use without user-induced variation ...STTR Phase I 2018 Department of DefenseDefense Health Agency
SBC: AUTONOMOUS HEALTHCARE INC Topic: DHP17B003
Drug dosingcan bemademore precise by using pharmacokineticand pharmacodynamicmodeling. Pharmacokinetics is thestudy of the concentration of drugs in tissueasafunction of timeand doseschedule,whereas pharmacodynamics is thestudy of therelationship between drugconcentration and drugeffect. By relating doseto resultant drugconcentration (pharmacokinetics)and concentration to effect (pharmacodynamics) ...STTR Phase I 2018 Department of DefenseDefense Health Agency