Award Data

Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause o

The proposed research and technical objectives in this project deal with computerized automatic delayering and polishing system that would be applicable to both commercial and government semiconductor device research and development with applications including Failure Analysis (FA), Fault Isolation (FI), and Reverse Engineering (RE) of semiconductor microelectronic devices. This project could hel ...

The objective of this project is to develop a compact and efficient avalanche photodiode (APD), operating between 200-250 nm, for implementation in the next generation bio-chem-detectors. The proposed detectors will be based on the AlGaN materials system and will be solar blind, highly sensitive, smaller, less expensive, and more robust than current UV detectors. Development of such APDs will enab ...

Opportunity: Guayule, a US native plant, is the only alternate rubber crop with an established, mechanized, agronomic system. Problem: Low rubber yields and lack of effective resin and bagasse coproduct valorization, have prevented widespread adoption by American farmers and processors. Rubber is only made when the cytoplasmic monomer pool (isopentenyl-pyrophosphate; IPP) is larger than that requi ...

Natural rubber is an essential manufacturing material that possesses performance properties that are superior to synthetic rubber for many product applications. However, natural rubber production is limited to a single species (rubber tree) in a limited geographic area (Southeast Asia) and is predicted to be incapable of meeting future demand. Producing rubber from another commercial crop such as ...

Most standard-of-care tools and techniques for evaluating neck disorders are subjective, unreliable, and do not provide actionable information for providers, payers, and organizations to deliver efficient and effective care. This lack of objective neck he

Traumatic brain injury is a common problem in both the military and civilian communities, but current treatment protocols are focused on managing symptoms and fail to prevent significant long-term repercussions. In the proposed program, Luna will demonstrate the feasibility of a liposome-based therapeutic delivery system capable of delivering hydrophilic and hydrophobic therapeutics to the traumat ...

The objective of this proposal is to examine the feasibility of defining and measuring key dimensions of an urban system to include its essential functions and networks, and whether they can be modelled in a computational framework for assessing robustness and resilience of DUTs (and their tipping points) under conditions of volatility and stress. This proposal will conduct a comprehensive review ...

This proposal is in response to the Defense Health Agency 2017 Phase I SBIR topic 17B-005.The approach is the use of a membrane oxygen pump using newly developed nano-thickness membranes with all the layers less than 1 micron total.Nanometer thickness membranes enable more oxygen output per surface area at temperatures of 300-600 C than current state-of-the -art 600-800 C membranes that are 50-300 ...

Clinicians have recognized that the nature of diseases can be highly individual resulting in different patterns of onset and progression. In turn, the response of an individual to drugs is also unique and governed by a variety of factors. Pharmacokinetic models represent the movement of a drug through the body, and personalized pharmacokinetic models aim to capture the unique responses of specific ...