Award Data

Adverse physiological events (PEs) have plagued warfighters piloting military aircraft, in particular PEs involving hypoxia and cockpit cabin decompression. Though there has been a large variety of research performed in trying to understand the problems and why theyre caused, there are inefficiencies due to the lack of standardized cross-laboratory protocols, procedures, and metrics. To address th ...

Airway compromise is the third leading cause of potentially preventable death on the battlefield. Current evaluation techniques of the airways associated with smoke inhalation injury are highly subjective and lack the sensitivity required of an accurate diagnostic and assessment tool. The problem of detection is further compounded by the late onset of symptoms that in many cases do not present unt ...

It is generally recognized that the human body transmits electro-magnetic fields (EMF). The Phase I program demonstrated a practical solution to detect these emissions. The technology was shown to be compatible for integration into wearable textiles. The Phase 2 program will focus on demonstrating the capability of discriminating between healthy and injury related EMF emissions such that it can be ...

Realistic surgical simulation requires a combination of representative tissue geometry, accurate tissue material properties and lifelike tool-tissue interaction forces. Recent advances in computational power and imaging modalities have provided the capability to represent the anatomical details required for surgical training; however, the mathematical models which govern the underlying tissue pro ...

BioMojo LLC and the Departments of Mathematics and Biomedical Engineering at the University of North Carolina Chapel Hill, will develop a preliminary bio mathematical model framework to represent how human tissues interact and behave at their boundaries. Tissue interaction properties (e.g. tensile, shear, friction, and so forth) of connective, epithelial, muscular, and nervous tissue including su ...

Most standard-of-care tools and techniques for evaluating neck disorders are subjective, unreliable, and do not provide actionable information for providers, payers, and organizations to deliver efficient and effective care. This lack of objective neck he

Current cervical spine assessment methodologies are focused on subjective measures (i.e. pain reports) and range-of-motion (ROM) measures that only measure maximum head excursion and reach, but not dynamic motion. Due to report bias and existing incentive

Thegoal is to develop asoftwaretool that implementsa novelapproach applicableto fitgeneral pharmacologic, toxicology, or other biomedical data, that mayexhibita non-monotonic dose-responserelationship for which thecurrent parametricmodels fail. Thesoftwareexplores dose-responserelationships using both monotonicand non-monotonicmodels,and estimates theassociated doseresponsecurves,which can further ...

Providing Army combat medics with meaningful experience in treatment of battlefield injuries is a particular challenge. Moulage has the potential to assist in acquiring what could otherwise be very hard-to-come-by preparatory experience for distressing real-life emergencies medics and soldiers may encounter in the field. However, current approaches to moulage are limited in their ability to reflec ...

Traumatic brain injury is a common problem in both the military and civilian communities, but current treatment protocols are focused on managing symptoms and fail to prevent significant long-term repercussions. In the proposed program, Luna will demonstrate the feasibility of a liposome-based therapeutic delivery system capable of delivering hydrophilic and hydrophobic therapeutics to the traumat ...