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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. NarcoBond: Opioid Targeted Biomimetic Nanosponges for Treatment of Opioid Overdose

    SBC: CiBots            Topic: NIDA

    Abstract We propose to develop a broad acute/sub-acute opioid drug detoxifying treatment for opioid overdose that can complement andamp; compensate for the deficiencies in nalaxone, using opioid-targeted biomimetic “nanosponges” that absorb overdosed opioids in the body. (Note: if this proof-of-concept is successful here, the approach may be tailored to other drugs-of-abuse.) Called “NarcoBo ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Technology-based Training Tool for an Empirically- Supported Group-Based HIV and STI Prevention Intervention for Juvenile Offenders

    SBC: Oregon Research Behavioral Intervention Strategies, INC            Topic: 102

    Summary AbstractYouth under ageinvolved in the criminal justice system are disproportionately minorities and affected by substance abusemental illnessand HIV STIMost young offenders are released on community supervision without the STImental healthor substance use screeningdiagnosisand treatment afforded detained youthdespite similar rates of risk behaviorTheir long term trajectory is poorthe cost ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Citizen-Science Technology for HealthyLiving at Home

    SBC: Access Sensor Technologies LLC            Topic: NIMHD

    Project Summary Environmental risk factors are attributable toof the chronic respiratory disease burden in the U Sand toof the burden from other non communicable diseasese gcancercardiovascular diseaseand diabetesExposure to environmental risk factors occurs through various forms of water and air pollutionwith a smaller attribution to sources like noiseradiationand physical hazardsMuch of this exp ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Therapeutic antibodies for treating chemotherapy induced peripheral neuropathic pain

    SBC: Abalone Bio, Inc.            Topic: 102

    SummaryTherapeutic antibodies for treating chemotherapy induced peripheral neuropathic pain Chroniclife disrupting painsuch as allodynia from chemotherapy induced peripheral neuropathyCIPNis difficult to manageIn this Phase I SBIRAbalone Bio proposes to develop a first in class specific CBagonist antibody that is BOTH an effective and safe analgesic against CIPN as well as a co therapy to enable o ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Translating an In-Person Brief, Bystander Bullying Intervention (STAC) to a Technology-Based

    SBC: KLEIN BUENDEL, INC            Topic: 102

    Project Summary While studies support the efficacy of comprehensiveschool wide interventions in reducing bullyingthese types of programs can require significant time and financial resources for implementationresulting in barriers to providing school based bullying preventionespecially in low income and rural communitiesAdditionallyalthough training bystanders to act asdefenderson behalf of targets ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Product Development of Intensity Modulation for Bolus Electron Conformal Therapy

    SBC: Decimal, LLC            Topic: 102

    Project Summary/Abstract Objective: This project aims to elevate electron beam therapy (EBT) technology, which provides effective radiation treatment for superficial cancers (depthandlt;6 cm), to that of other external beam radiotherapies (XRT), e.g. x-rays and protons, by bringing electron intensity modulation into the clinic. Challenge: Approximately 10% of radiotherapy patients (173,000 in U ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A novel smartphone-based tool to quantify dual-task gait performance for concussion assessment

    SBC: Control One LLC            Topic: NINDS

    Project Summary Sport related concussions are a serious public health concern in the United Stateswithtomillion concussions reported annuallyYoung athletes who suffer a concussion experience quality of life alterationswith cognitive impairmentreduction in balance or coordinationand memory lossUnfortunatelyseveral factors limit the ability to accurately and feasibly evaluate the deleterious effects ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Highly accurate small-RNA sequencing of single cells (RealSeq-SC)

    SBC: REALSEQ BIOSCIENCES, INC.            Topic: 172

    Abstract The goal of this grant application is to develop the first commercially available library preparation kit for profiling small RNAs from single cells using NGS methods. Single-cell analyses of mRNA have allowed the identification of crucial differences between cells that were otherwise considered identical. These findings have shown that there is intrinsic “noise” in the regulation of ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Therapeutic in Situ Analgesic Implant for improved Oral-Facial Post-Operative Pain Outcomes

    SBC: Epigen Biosciences, Inc.            Topic: NIDCR

    PROJECT SUMMARY Analgesia for post operative populations remains a significant health need that calls for innovative therapies which improve both safety and outcome measuresRecent FDA drug safety warnings and studies focusing on post operative analgesia have highlighted the imperative need for new approaches that can be utilized for common clinical scenariosAccordinglynovel treatment options that ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A single dose long-acting non-addictive polymer conjugate formulation of buprenorphine that provides immediate and prolonged analgesia for post-operative pain

    SBC: SERINA THERAPEUTICS INC            Topic: NINDS

    PAProject Summary Abstract SERis a long acting polymer pro drug of buprenorphine that is being developed to treat postoperative pain following major surgeries such as bunionectomyabdominoplastythoracotomy and knee and hip surgerySERhas no biological activity by itselfbut when administered in vivo by subcutaneous injection it enters the vascular compartment where a plasma esterasebutyrylcholinester ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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