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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Bedside Relational Agent to Improve Hematopoietic Cell Transplantation Outcomes in Cancer Patients

    SBC: CARE.COACH CORPORATION            Topic: 101

    Abstract Deliriuma major cause of fallscan occur in as many asof cancer patients undergoing stem cell transplantationresulting in up totimes greater chance of dyingDelirium risk can be mitigated and many other outcomes of stem cell transplants can be improved through behavioral interventions delivered at the bedside through conversationimageryand audioHowevertraditional means of delivering these i ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A Better Mechanism for Controlled Nanopore Translocation

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: 172

    Project Summary Enabling high accuracy nanopore based strand sequencing has the potential to improve the understanding of long range genomic relationships and processes andbased on its accessibilityenable the associated clinical and diagnostic applicationsthe fastest growing sequencing sectorUnfortunatelyit is commonplace for nanopore sequencing error rates to exceedand higher accuracy is needed t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Accelerating Site-specific Characterization of Protein Therapeutics with Novel Machine Learning Methods

    SBC: MASSMATRIX INC            Topic: 400

    PROJECT SUMMARYABSTRACT TitleAccelerating Site specific Characterization of Protein Therapeutics with Novel Machine Learning Methods The project seeks to improve reliability and speed up the development of life saving and life enhancingprecisionprotein therapeutics and magnify the positive impact of biomedical research and education worldwideleading to a quantum leap in our understanding of the mo ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Accurate and efficient density functional theory calculations of intermolecular interactions and conformational energies

    SBC: Q-CHEM INC            Topic: 300

    Abstract Biophysical properties can be computer-modeled using quantum mechanics (QM). While vastly more computationally costly than molecular mechanics (MM), QM methods are essential for bond-breaking and/or high accuracy. Indeed, QM methods have advanced with exciting, (and ongoing) improvements in the accuracy of density functional theory (DFT). These DFT improvements could open new applications ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Accurate, long read length, whole human genome sequencing under 100

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): The aim of this project is to investigate a simple method for slowing down the rate of electrophoretic translocation of DNA through a nanopore. Unique modulations of current across nanopores produced by individual basesduring such translocation forms the basis of DNA nanopore sequencing. The nanopore method requires very simple sample preparation with potential ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. A CD8+ T cell diagnostic to identify children with pulmonary tuberculosis

    SBC: ViTi, Inc            Topic: NIAID

    DESCRIPTION provided by applicant Tuberculosis TB disease which results from infection with Mycobacterium tuberculosis Mtb is a leading cause of infectious morbidity and mortality in children andlt years old worldwide In TB endemic regions in which the vast majority of the worldandapos s annual million adult cases of TB disease reside children andlt years old account for ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. A Cell-based Assay for Botulinum Neurotoxin Detection and Development

    SBC: Q-Track Corporation            Topic: NIEHS

    DESCRIPTION (provided by applicant): The proposed effort aims to dramatically enhance the realism of radiation safety training for Emergency Responders, both First Responders, as well as Skilled Support Personnel. The goal is to develop andevaluate realistic dosimetry simulation or Dosimulation tools. These Realistic, Accurate Dosimulation (RAD) tools will be the centerpiece for ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. A Clinical Study of Latiglutenase as a Treatment for Symptom Reduction for Celiac Disease

    SBC: IMMUNOGENICS LLC            Topic: NIAID

    Project Summary AbstractThe goal of this work is to develop a therapeutic drug that will protect individuals with celiac diseaseCDfrom intestinal and symptomatic distress they suffer due to minute ingestion of gluten proteinCD is an autoimmune disorder affecting the small intestineafflicting aboutof the world s populationfor which there is no known cureCurrently the only therapeutic option to avoi ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. A Clinical Study of Latiglutenase as a Treatment for Type 1 Diabetics with Celiac Disease

    SBC: IMMUNOGENICS LLC            Topic: 300

    Project Summary The goal of this work is to evaluate the efficacy of a therapeutic agent for protecting individuals with TypediabetesT Dand celiac diseaseCDfrom intestinal and symptomatic distress they suffer due to minute ingestion of gluten proteinBoth T D and CD are lifelong autoimmune diseases whose management is anchored upon very restrictive and distinct dietsThe co morbidity of these two di ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A compact, modular two-photon fiber-coupled microscope for in vivo all-optical electrophysiology

    SBC: INTELLIGENT IMAGING INNOVATIONS, INC.            Topic: 101

    Good methods to interrogateand ideally perturbneural systems at the network level have been elusive until recentlyThe advent of biochemical breakthroughsnamely neuronally targeted genetically encoded calcium reporterssuch as GCaMPand light activated channelssuch as channelrhodopsinhave enabledall opticalelectrophysiology where experiments can be conducted that involve simultaneousor closely sequen ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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