You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. IMPACT-Instrument to Measure Pain and Assess Correlation to Treatment. Create a smartphone pupillometry to objectively determine the presence of acute pain, evaluate opioid as the treatment for pain.

    SBC: BENTEN TECHNOLOGIES, INC.            Topic: NIDA

    PROJECT SUMMARY ABSTRACT While patient self report of pain is currently the gold standard of pain measurementaccurate self reports of pain may not be feasible in critically ill patients who are sedated and intubatedunconscious patientsor patients who are unable to verbally communicate their painCurrent research has shown that pupillary dilationPDis a reliable indicator of acute painand that measur ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. AI-enabled fully automated retinal image-based biomarkers for mild cognitive impairment and neurodegenerative disorders

    SBC: EYENUK, INC.            Topic: NINDS

    AbstractIn this SBIR projectwe present EyeQuantan AI enabled fully automated tool to compute retinal image based biomarkers for mild cognitive impairment and neurodegenerative disordersThe largegrowingand aging population is likely to lead to a dramatic increase in the number of people at risk for dementia and other cognitive disorderswith more thanmillion people expected to be affected byVascular ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Targeting PDGFs for Potential Treatment of Proliferative Vitreoretinopathy

    SBC: APTITUDE MEDICAL SYSTEMS INC            Topic: NEI

    Abstract SignificanceProliferative vitreoretinopathyPVRis a blinding orphan indication that occurs inof patients receiving rhegmatogenous retinal reattachment surgeryand accounts forof all primary surgical failuresPVR is characterized by migration and proliferation of ectopic cells beneath or on the surface of the retinawhich then assemble into a membranecausing retinal traction and detachmentSinc ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Treatment of Chemotherapy-Induced Peripheral Neuropathy via Genetic Repression of Sodium Channels

    SBC: NAVEGA THERAPEUTICS, INC.            Topic: 102

    Project Summary Abstract The goal of this project is to develop a therapeutic product that relieves chemotherapy induced peripheral neuropathyCIPNin a non permanentnon addictive and long lasting manner to improve the quality of life of cancer patientsCurrently more thanmillion Americans andbillion people worldwide suffer from chronic painVoltage gated sodium channels transmit pain signals in nocic ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. BEST-OUD: Behavioral Economic Screening Tool of Opioid Use Disorder for use in clinical practice

    SBC: BEAM Diagnostics, Inc.            Topic: 41

    PROJECT SUMMARY Fatal overdose from opioid misuse is one of the most pressing issues affecting the modern worldAs one of the nation s leading preventable causes of deatha critical line of defense against opioid use disorderOUDmust be standardized screening provided by the patient s primary care physicianpsychiatristand or counselorStandardized screening methods for opioidshoweverare simply inferio ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Biosensor and Eyedrop Bottle Technologies for Glaucoma Adherence Monitoring

    SBC: Toromedes, Inc            Topic: NEI

    Project SummaryNon adherence with prescribed systemic drugs leads to poor outcomes and increases the cost of healthcareGlaucomathe leading cause of irreversible blindnessaffects more thanmillion people worldwideLowering intraocular pressurethe only proven method of delaying both the development and progression of glaucomais typically done with topical administration of eye dropswhich has notorious ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Development of An Oral,Brain/Eye penetrating, Second Generation TTR Stabilizer for The Treatment of Transthyretin Amyloidoses

    SBC: PROTEGO BIOPHARMA, INC.            Topic: NINDS

    The TTR Amyloidoses (ATTR) are rare, progressive, ultimately fatal diseases that compromise the function of multiple organs, causing a wide range of debilitating clinical symptoms. ATTR is caused by the dissociation of the tetrameric transthyretin (TTR) protein, leading to misfolding and aggregation of the released monomers with toxic oligomer formation and subsequent tissue deposition as physiolo ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. An Instrument to Assess the Functional Impact of Chronic Pain

    SBC: BARRON ASSOCIATES, INC.            Topic: 999

    Project Summary Abstract Evaluation and treatment for chronic pain are major contributors to rising healthcare costsAlthough accurate assessment of pain and function is the cornerstone to successful chronic pain managementsystematicobjective assessment of the functional impact of pain remains exceptionally challenging in practiceThe intricate nature of chronic pain demands a comprehensivemulti mod ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Pharmacokinetic and toxicology studies of AYX2, a transcription factor decoy, non-opioid, disease modifying drug candidate for the long-term treatment of chronic pain

    SBC: Adynxx, Inc.            Topic: NINDS

    RESEARCH AND RELATED OTHER PROJECT INFORMATIONPROJECT SUMMARYABSTRACTFunding OpportunityPAPI NameMametJulienAs described by the HEAL Initiative Notice NOT NSthere currently exists an urgent unmet need for enhanced pain management in the form of safeeffectivenon opioid pain treatmentsChronic focal neuropathic painwhich includes pain etiologies such as radiculopathy and radiculitisfocal peripheral n ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Supplement to Promote Diversity and Inclusion, Female Scientist

    SBC: NAVEGA THERAPEUTICS, INC.            Topic: NINDS

    Project Summary/Abstract Currently more than 100 million Americans and 1.5 billion people worldwide suffer from chronic pain. This is more than cancer, diabetes, and heart disease combined. Voltage-gated sodium channels are responsible for the transmission of pain signals. Nine genes have been identified, each having unique properties and tissue distribution patterns. Genetic studies have correlat ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government