Award Data

The goal of medical simulation-based training such as high-fidelity manikin simulators, part task trainers, and screen-based virtual patients, is to approximate real-life treatment experiences without risk to live patients. While the use of sensors has ma

Current methods to discern the differentiation state of stem cells are time-consuming, labor-intensive, costly, invasive, and consequently, ill-suited for clinical applications. To overcome these limitations, we propose to develop a microfluidic stem cell analyzer for accurate, non-invasive identification of the cell differentiation state in conjunction with automated cell sorting at high-throughp ...

Care for the wounded Warfighters in austere and remote settings makes medical knowledge, skills and efficiency of the military medical professional paramount. For wounds that extend deep into internal anatomy, proper visualization of internal anatomy can

The company has developed a silk-derived protein (SDP) for use as a novel ophthalmic formulation excipient that will help to treat the ocular injuries and dry eye pathology that affects over 40 million Americans annually and hundreds of millions of people worldwide. The SDP excipient is designed to enhance tear formulation comfort, longevity, and overall ocular health. This proposal builds on the ...

Sweat contains biomarkers that give an indication of human cognitive levels. In this SBIR project TDA Research is developing a modular sweat sensor patch that has the capability to not only carry out real-time monitoring of select biomarkers, but also to

The published data has demonstrated that the currently available resuscitation fluids have detrimental effects on trauma outcomes.By addressing these deficiencies it is expected that the outcomes will improve. The crystalloid based resuscitation fluid in development by GanD Inc. has been designed to address all of the shortcomings of the currently available solutions.The solution, GND-001, is a cr ...

Problem: Currently available resuscitation fluids have been shown to induce detrimental effects on trauma outcomes. Objective: The objective of this proposal is to use the data from the successful Phase 1 studies to guide the continued development and te

The Defense Health Agency (DHA) has identified electrotextiles as a potential means of unobtrusively monitoring health and detecting injury events for military personnel. As such, DHA seeks to understand how e-textile constructs might be best leveraged to sense potential injury events such that individualized care may be administered to support both in-combat self-sufficiency and long-term resilie ...

Wearable devices have grown to meet the demand for continuous, noninvasive vital signs monitoring in the military and civilian health care markets.These devices have largely excluded pulse oximetry because non-traditional sites, such as the chest, arm and legs, pose a challenge. We have previously demonstrated the ability to accurately monitor pulse oximetry on the chest, arms and calf.This projec ...

Successful completion of the previous Phase I study and additional clinical trials has demonstrated that percutaneous peripheral nerve stimulation (PNS) has the potential to provide non-opioid pain relief and improvements in function to injured Service members, Veterans, and civilians. Feedback from military advisors, clinicians, and patients have identified challenges that must be addressed to tr ...