Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Product Development of Intensity Modulation for Bolus Electron Conformal Therapy

    SBC: Decimal, LLC            Topic: 102

    Project Summary Abstract ObjectiveThis project aims to elevate electron beam therapyEBTtechnologywhich provides effective radiation treatment for superficial cancersdepthandltcmto that of other external beam radiotherapiesXRTe gx rays and protonsby bringing electron intensity modulation into the clinicChallengeApproximatelyof radiotherapy patientsin USA annuallyreceive EBT for a portion of their t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Selective Kv7.2/3 activators for the treatment of neuropathic pain

    SBC: Knopp Biosciences            Topic: 106

    Project Summary The successful management of chronic pain is inadequate in many patients and has contributed to the abuse of and addiction to opioidsa continuing major public health crisis in the United States and worldwideThe development of non addictive pain therapeutics can help counter opioid addiction and benefit patientsincluding those who suffer from neuropathic painand in particular diabet ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. A single dose long-acting non-addictive polymer conjugate formulation of buprenorphine that provides immediate and prolonged analgesia for post-operative pain

    SBC: SERINA THERAPEUTICS INC            Topic: NINDS

    PAProject Summary Abstract SERis a long acting polymer pro drug of buprenorphine that is being developed to treat postoperative pain following major surgeries such as bunionectomyabdominoplastythoracotomy and knee and hip surgerySERhas no biological activity by itselfbut when administered in vivo by subcutaneous injection it enters the vascular compartment where a plasma esterasebutyrylcholinester ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Minimally Invasive Intercostal Nerve Block Device to Treat Severe Pain and Reduce Usage of Opiates

    SBC: Thermaquil, Inc.            Topic: 106

    Project SummaryMost of thek Americans who undergo thoracotomy each year receive opiates to reduce postoperative pain because clinicians have few non addictivecost effective choices to control the severe pain patients often experience in the first two weeks after surgeryManaging pain post thoracotomy is critical to enable patients to take deep breaths and removevia coughinglung secretions that othe ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Gra

    SBC: Mosaix Software, Inc.            Topic: NCIPC

    Project Summary Abstract This is the phase II application of a NIDA funded SBIR grant titled Demand Reduction Smart Tool for Analysis and Research STAR NIDA Grant R DA A The goal of Phase II is to develop a commercial grade Self Service Visual Analysis SSVA tool based on Phase I STAR Prototype empowering decision makers and managers in drug demand reduction field to make data driven decisions in m ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Associating Clinical Decision Support Use with Clinical Outcomes in a Visual Analytics Display

    SBC: PHRASE Health, INC.            Topic: NLM

    Project Summary Abstract Clinical decision supportCDSis a process for enhancing health related decisions and actions with pertinentorganized clinical knowledge and patient information to improve healthcare deliveryFor exampledoctors may have trouble remembering to order all guideline recommended care for sepsisCDS delivered via an order set in the electronic health recordEHRcan simplify this proce ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Stem Cells for Treating Acute Stroke

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: 999

    ABSTRACT SUMMARY In previous studies we identified novel non hematopoietic umbilical cord blood stem cellsnhUCBSCsthat could be expanded to high passages and exhibit restorative properties following ischemic brain injury repairWe found that the high passaged cells were equivalentif not even betterthan the low passaged nh UCBSCsThis finding suggests that these cells can serve as a source of highly ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Nonalcoholic Steatohepatitis Therapies from the Ubiquitin Pathway

    SBC: Progenra, Inc            Topic: 300

    Nonalcoholic steatohepatitisNASHis a serious health condition associated with the accumulation of lipids in the liver which leads to chronic inflammationThis inflammation can predispose affected individuals to serious downstream health problems including cirrhosis and hepatocellular carcinomaNASH occurs in a wide variety of patients but has a number of known risk factorsincludingobesityglucose int ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. A SAFE AND COMPACT NEONATE TO ADULT NEUROIMAGING MRI SYSTEM

    SBC: ADVANCED IMAGING RESEARCH, INC.            Topic: 101

    NIH SBIR PAw o Clinical Trials A Safe and Compact Neonate to Adult Neuroimaging MRI System The intriguing human brain is the most imaged end organ non invasivelywithout ionizing radiation using magnetic resonance imagingMRIHigh spatial resolution brain MRI is an established diagnostic tool to assess injury mechanisms affecting newborn growth and the adult human connectomeTo predict neurodevelopmen ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Prevention of renarcotization from synthetic opioids

    SBC: Consegna Pharma Inc.            Topic: NIDA

    PROJECT SUMMARY ABSTRACT In Octoberthe U SGovernment declared the current opioid epidemic the worst drug crisis in American historySynthetically derived opioids such as fentanyl and fentanyl derivatives have been at the forefront of this public health emergencyexhibiting the highest year to year contribution to overdose deathsWhile the mu opioid receptorMORantagonist naloxone has proven invaluable ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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