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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Product Development of Intensity Modulation for Bolus Electron Conformal Therapy

    SBC: Decimal, LLC            Topic: 102

    Project Summary/Abstract Objective: This project aims to elevate electron beam therapy (EBT) technology, which provides effective radiation treatment for superficial cancers (depthandlt;6 cm), to that of other external beam radiotherapies (XRT), e.g. x-rays and protons, by bringing electron intensity modulation into the clinic. Challenge: Approximately 10% of radiotherapy patients (173,000 in U ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Selective Kv7.2/3 activators for the treatment of neuropathic pain

    SBC: Knopp Biosciences LLC            Topic: 106

    Project Summary The successful management of chronic pain is inadequate in many patients and has contributed to the abuse of and addiction to opioidsa continuing major public health crisis in the United States and worldwideThe development of non addictive pain therapeutics can help counter opioid addiction and benefit patientsincluding those who suffer from neuropathic painand in particular diabet ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. A single dose long-acting non-addictive polymer conjugate formulation of buprenorphine that provides immediate and prolonged analgesia for post-operative pain

    SBC: SERINA THERAPEUTICS INC            Topic: NINDS

    PAProject Summary Abstract SERis a long acting polymer pro drug of buprenorphine that is being developed to treat postoperative pain following major surgeries such as bunionectomyabdominoplastythoracotomy and knee and hip surgerySERhas no biological activity by itselfbut when administered in vivo by subcutaneous injection it enters the vascular compartment where a plasma esterasebutyrylcholinester ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Customer discovery for minimally invasive nerve block device to treat severe pain and reduce usage of opiates

    SBC: Thermaquil, Inc.            Topic: 106

    Abstract: Thoracotomy is one of the most painful surgical procedures and patients are at high risk of developing opioid addiction. Recent studies have shown 1 in 7 patients became new persistent opioid users after physical recovery from the surgery was complete. The largest risk factor for opioid addiction is being prescribed opioids in the first place, and Thermaquil wants to reduce this incidenc ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Associating Clinical Decision Support Use with Clinical Outcomes in a Visual Analytics Display

    SBC: PHRASE HEALTH, INC.            Topic: NLM

    Project Summary Abstract Clinical decision supportCDSis a process for enhancing health related decisions and actions with pertinentorganized clinical knowledge and patient information to improve healthcare deliveryFor exampledoctors may have trouble remembering to order all guideline recommended care for sepsisCDS delivered via an order set in the electronic health recordEHRcan simplify this proce ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Stem Cells for Treating Acute Stroke

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: 999

    ABSTRACT SUMMARY In previous studies we identified novel non hematopoietic umbilical cord blood stem cellsnhUCBSCsthat could be expanded to high passages and exhibit restorative properties following ischemic brain injury repairWe found that the high passaged cells were equivalentif not even betterthan the low passaged nh UCBSCsThis finding suggests that these cells can serve as a source of highly ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Nonalcoholic Steatohepatitis Therapies from the Ubiquitin Pathway

    SBC: Progenra, Inc            Topic: 300

    Nonalcoholic steatohepatitisNASHis a serious health condition associated with the accumulation of lipids in the liver which leads to chronic inflammationThis inflammation can predispose affected individuals to serious downstream health problems including cirrhosis and hepatocellular carcinomaNASH occurs in a wide variety of patients but has a number of known risk factorsincludingobesityglucose int ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. A SAFE AND COMPACT NEONATE TO ADULT NEUROIMAGING MRI SYSTEM

    SBC: ADVANCED IMAGING RESEARCH, INC.            Topic: 101

    NIH SBIR PA-18-871 w/o Clinical Trials A Safe and Compact Neonate to Adult Neuroimaging MRI System The intriguing human brain is the most imaged end-organ non-invasively, without ionizing radiation using magnetic resonance imaging (MRI). High spatial resolution brain MRI is an established diagnostic tool to assess injury mechanisms affecting newborn growth and the adult human connectome. To predic ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Prevention of renarcotization from synthetic opioids

    SBC: CONSEGNA PHARMA INC            Topic: NIDA

    PROJECT SUMMARY/ABSTRACT In October 2017, the U.S. Government declared the current opioid epidemic the worst drug crisis in American history. Synthetically derived opioids such as fentanyl and fentanyl-derivatives have been at the forefront of this public health emergency, exhibiting the highest year-to-year contribution to overdose deaths. While the mu opioid receptor (MOR) antagonist naloxone ha ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Drug Eluting Embolization Coils for Improved Treatment of Intracranial Aneurysms

    SBC: Ancure, LLC            Topic: 105

    PROJECT SUMMARY Brain aneurysms are a high-risk condition in which bulging blood vessels in the brain are at risk of rupture. The mortality rate after rupture is 40-60% if no treatment is administered. Current treatment for both ruptured and unruptured aneurysms includes surgical clipping (exovascular therapy) and catheter-based intervention (endovascular therapy). In endovascular therapy, which i ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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