Award Data

Project Summary/Abstract Objective: This project aims to elevate electron beam therapy (EBT) technology, which provides effective radiation treatment for superficial cancers (depthandlt;6 cm), to that of other external beam radiotherapies (XRT), e.g. x-rays and protons, by bringing electron intensity modulation into the clinic. Challenge: Approximately 10% of radiotherapy patients (173,000 in U ...

PAProject Summary Abstract SERis a long acting polymer pro drug of buprenorphine that is being developed to treat postoperative pain following major surgeries such as bunionectomyabdominoplastythoracotomy and knee and hip surgerySERhas no biological activity by itselfbut when administered in vivo by subcutaneous injection it enters the vascular compartment where a plasma esterasebutyrylcholinester ...

The Air Force has a need for low-cost, short takeoff and landing vehicles to provide recovery and transport support in contested areas while minimizing the required number of operational personnel. An autonomous vehicle capable of 100 miles operational radius, cruise speed greater than 100 kts at 4000 ft, and takeoff/landing zone of 50 ft x 50 ft is desired to perform combat search and rescue, as ...

ABSTRACT SUMMARY In previous studies we identified novel non hematopoietic umbilical cord blood stem cellsnhUCBSCsthat could be expanded to high passages and exhibit restorative properties following ischemic brain injury repairWe found that the high passaged cells were equivalentif not even betterthan the low passaged nh UCBSCsThis finding suggests that these cells can serve as a source of highly ...

NIH SBIR PA-18-871 w/o Clinical Trials A Safe and Compact Neonate to Adult Neuroimaging MRI System The intriguing human brain is the most imaged end-organ non-invasively, without ionizing radiation using magnetic resonance imaging (MRI). High spatial resolution brain MRI is an established diagnostic tool to assess injury mechanisms affecting newborn growth and the adult human connectome. To predic ...

The importance of determining crystallographic orientation information over large areas has existed within the materials science community for solutions to a variety of applications in aerospace and otherwise since the connection of MTRs and material performance was discovered, but it isn’t until recently that a feasible solution has existed. In this work, MRL will demonstrate the feasibility of ...

In the naval aircraft many disparate materials are subject to galvanic corrosion, due to the marine environment. Some of these aircraft have hybrid (carbon fiber composite/aluminum) designs that exhibit accelerated corrosion damage, compared to legacy all-metal frames, due to galvanic interaction between the fastener, the composite skin, and the aluminum frame. In the Phase I SBIR program, UES Inc ...

The aim of this project is to develop an audiometric testing response simulatorSimulators are quickly becoming a critical component in the training of professionals across all fieldsThe proposed simulator is intended to be used in any environment where behavioral response audiometric testing is conductedthe foundation of most auditory assessmentsThe simulator will have the capability to connect wi ...

SUMMARY Despite significant advances in the surgical and medical management of congenital heart diseasecongenital cardiac anomalies remain a leading cause of death in the newborn periodMost severe forms of congenital heart disease require multiplestaged surgical interventionsA significant source of the heightened morbidity and mortality associated with these operations is the development of cardia ...

Rotary cannon type weapons, such as the M197 electric cannon, currently require servicing every 28 days in order to remove abrasive particulate and to relubricate the rotary drum. The Navy is currently seeking a one-time application coating, applied at the time of manufacturing or retrofit, which will at least double the time between servicing to 56 days or more. Mainstream Engineering proposes to ...