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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. IGF::OT::IGF SBIR TOPIC 379: DIGIBIOMARC: DIGITAL BIOMARKERS FOR CLINICAL IMPACT- MOONSHOT PROJECT(FAST TRACK)

    SBC: Medable Inc.            Topic: NCI

    The overall objective of this Fast Track SBIR contract project is to develop DigiBioMarCTMDigital BioMarkers for Clinical Impacta scalable and flexible cloud based platform to capture and analyze wearableimplantableor external device dataThis platform also provides an informatics tool for automated data aggregationintegrationand machine learning algorithmsIt is based on the scalable user centered ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Structure-based discovery of dopamine D1 receptor selective small molecule ligands

    SBC: CONFOMETRX, INC.            Topic: 101

    Dopamine receptors are a family of G protein-coupled receptors (GPCRs), and can be further divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) subfamilies. In this proposal, we focus on D1 receptor, which is widely expressed in brain at high levels. Modulation of D1 activity is implicated in the treatment of many psychiatric and neurological disorders, such as schizophrenia, attention def ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Rapid and Simple Paper Strip Test for the Multiplexed Detection of Gastrointestinal Pathogens at the Point-of-Need

    SBC: Godx Inc.            Topic: 950

    PROJECT SUMMARY GoDx, Inc. has been developing a prototype multiplexed paper strip device for the detection of the DNA and RNA of gastrointestinal pathogens at the point-of-need in andlt; 30 minutes with funding from the NCATS SBIR parent grant TR 001912. We have used the same platform technology we are developing in the parent grant to develop a rapid (andlt;30 minute), low-cost and instrument-fr ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. THIS SBIR PHASE I CONTRACT IS FOR A WEARABLE ALCOHOL BIOSENSOR THAT QUANTIFIES BAC IN REAL TIME.

    SBC: DeLeon, Augustina S            Topic: NIAAA

    Technology validation study of a wearable NIR spectrometer to quantify BAC in real time

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. A point of care test for TB antibiotic concentration in blood

    SBC: NANOCOMPOSIX, INC.            Topic: NIAID

    TuberculosisTBis one of the topcauses of death worldwideTB treatments include combinations of multiple antibiotics and dosage levels over a long period of timeOften the dose must be adjustedLow antibiotic blood concentrations may cause slow responseprolonged infection or treatment failureand the TB strain may acquire drug resistancetoo high and toxicity may be an issueCurrent technologies for meas ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. POC Diagnostic for Gonorrhea and Determination of Antimicrobial Susceptibility

    SBC: Visby Medical, Inc.            Topic: NIAID

    VisbyFormally know as Click Diagnosticshas developed a PCR based rapiddisposablepoint of care test that automatically performs sample processingPCR amplificationand amplicon detectionLeveraging the existing platformClick willfrom a single urogenital sampledetect NG and determine whether the infecting strain is susceptible to three classes of antibioticsciprofloxacincefiximeor a novel antibiotic zo ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Electrochemical aptasensor for Anti-Tuberculosis antibiotic quantification

    SBC: GUILD ASSOCIATES INC            Topic: NIAID

    Specific AimsIn Phase I of this SBIRwe will complete three specific aimssynthesize stable combination adjuvant formulations that are compatible with an HVLP antigenidentify the combination adjuvant properties that augment the safe and durable immunity to Handdemonstrate the superior protective benefit of the new combination adjuvant over existing adjuvant solutions for pandemic influenza vaccinesI ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. New Carriers Used as Adjuvants for Controlled HIV Immunogen Delivery into Targeted Antigen Presenting Cells

    SBC: NANOCOMPOSIX, INC.            Topic: NIAID

    Despite the global impacts of HIV on human healthwith an estimatedmillion new cases each year andmillion people living with HIVan effective vaccine has not been developedThere are many challenges for HIV vaccine development including the virus s rapidly changing surface immunogens and the early integration of the virus into the host s genomeTo overcome these challengesa mesoporous silica adjuvant ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Mobile Health Point-of-Care Diaagnostics for Malaria

    SBC: CHROMOLOGIC LLC            Topic: NIAID

    A resurgence of malaria infections has occurred in the USprimarily due to increasing global travelOnly wide spread screenings and treatments of endemic populations can prevent the return of malaria endemicityCurrentlythere is no diagnostic test that meets the need of highly sensitive malaria screening tool for low resource settingsTo address this needChromoLogic proposes to develop the Quick Mag p ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Evaluation of VesiVax Adjuvant Formulations for HIV Vaccines

    SBC: MOLECULAR EXPRESS, INC            Topic: NIAID

    This proposal aim to develop a VesiVaxplatform based liposomal vaccine that can co formulate the HIV antigenHIV Env gpAwith various immunotimulatory adjuvant moleculesIAMsThe IAMs that we will formulate with the antigen includeslipidated tucaresolmuramyl tripeptide phosphatidylethanolaminePam CAGmonophosphoryl lipid AdsRNAandcyclic dinucleotidesThe formulations will be evaluated in miceand selecte ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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