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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. STTR Phase II: Termite-derived enzymatic tree bio-herbicides

    SBC: Ento Bio LLC            Topic: CT

    The broader impact and commercial potential of this Small Business Technology Transfer and Research (STTR) project is a method to control invasive or otherwise unwanted trees and shrubs in an ecologically friendly manner with a biodegradable product. This will reduce the quantity of synthetic herbicides and/or synthetic herbicide adjuvants currently applied to control woody plants. This is especia ...

    STTR Phase II 2017 National Science Foundation
  2. Tissue Engineered Intestine

    SBC: Nanofiber Solutions, Inc.            Topic: 300

    PROJECT ABSTRACT Short bowel syndromeSBSis a major clinical problem affecting newbornschildren and adultsfor which there is currently no known cureThe disorder results from the functional or anatomic loss of extensive segments of small intestine rendering the intestinal absorptive capacity severely compromisedSBS is clinically defined by malabsorptiondiarrheasteatorrheafluid and electrolyte distur ...

    STTR Phase II 2017 Department of Health and Human Services
  3. A phase IIA trial for the safety and tolerability of CD24Fc in prophylaxis of graft vs host disease.

    SBC: Oncoimmune Inc            Topic: 102

    Project Summary AbstractAcute graft versus host diseaseaGVHDis a principal contributor to transplant related mortalityTRMand develops in approximatelyof recipients receiving unrelated donor hematopoietic stem cell transplantationHSCTdespite standard immunosuppressive prophylaxisThusnovel GVHD prophylaxis treatments which successfully attenuate aGVHD and related complications such as infection are ...

    SBIR Phase II 2017 Department of Health and Human Services
  4. CD206 Targeted Therapy for Kaposi Sarcoma and Tumor Associated Macrophages

    SBC: Navidea Biopharmaceuticals, Inc.            Topic: 102

    Summary AbstractKaposi sarcomaKSis a potentially life threatening consequence of immunosuppression in patients that are infected with human herpes virusHHVMost KS occurs in patients with acquired immunodeficiency syndromeAIDSCurrent KS therapies have limited efficacy and serious off target toxicitiesNavidea has been developingmTc tilmanocepta wholly synthetic molecular construct that binds with ve ...

    SBIR Phase II 2017 Department of Health and Human Services
  5. NONA Repair of Composite Structures

    SBC: Cornerstone Research Group, Incorporated            Topic: T1202

    Supporting aerospace mission readiness, a system is needed that allows for composite repairs without the current roadblocks imposed by ovens, autoclaves, and expensive tooling. Cornerstone Research Group (CRG), its subsidiary NONA Composites, and the University of Dayton Research Institute (UDRI) presents NASA with the opportunity to obtain a rapid and robust method for on-site composite structura ...

    STTR Phase II 2017 National Aeronautics and Space Administration
  6. Unified In-Space Propulsion Framework for Prediction of Plume-Induced Spacecraft Environments

    SBC: CFD Research Corporation            Topic: T102

    Chemical contamination of spacecraft components as well as thermal and force loading from firing liquid propellant thrusters are critical concerns for in-space propulsion applications. Gas molecular contamination and liquid droplet deposition due to incomplete combustion threaten to damage surface materials, sensitive instruments and optical sensors, and poses major risks for mission success. Liqu ...

    STTR Phase II 2017 National Aeronautics and Space Administration
  7. Empirical Optimization of Additive Manufacturing

    SBC: Universal Technology Corporaration            Topic: T1204

    In this Phase II STTR project, the proposed collaborative effort between UTC, AFIT, and ULRF represents a crucial step forward for AM.  UTC’s unique AM optimization and process control framework, constructed entirely from experimental sensor data collected in-situ, will finally transfer technology from our SLM test bed system to state-of-the-art and commercial-grade systems, including a ...

    STTR Phase II 2017 National Aeronautics and Space Administration
  8. Development of a Fully Humanized Antibody for Treating Lung Emphysema

    SBC: Allinaire Therapeutics, LLC            Topic: NHLBI

    Project Summary COPD is a common and serious disease with no cure that is characterized by chronicprogressive lung damagea decline in pulmonary function and quality of lifeand often deathThe two major clinical features of COPD are emphysema and chronic bronchitisCOPD is mainly associated with exposure to cigarette smokeCShoweveraboutof COPD patients have a genetic deficiency of alphaantitrypsinAAT ...

    SBIR Phase II 2017 Department of Health and Human Services
  9. Commercialization of an MRI contrast agent for differential diagnosis of prostate cancer.

    SBC: MOLECULAR THERANOSTICS, LLC            Topic: 102

    AbstractProstate cancer is a highly heterogeneous disease and the second most cause of cancer death of men in the USCurrent methods to assess prostate cancer risk combine prostate specific antigenPSAscreening and random prostate biopsyUnfortunatelythis strategy fails to reveal the lesion s location and does not accurately differentiate between aggressive and non aggressive prostate cancersAs a res ...

    SBIR Phase II 2017 Department of Health and Human Services
  10. Re-Entrant Jet Measurement During Large-Scale Gas Bubble Collapse

    SBC: Engineering and Scientific Innovations, Inc.            Topic: N153133

    Understanding the dynamics of the re-entrant jet phenomenon is of great interest for the particular applications where it may occur. In spite of this, the dynamics of large-scale bubble collarless are not understood. Engineering & Scientific Innovations (ESI) is proposing the use of the same methods applied to quantitatively evaluate a hydrodynamic ram event to the re-entrant jet problem.

    SBIR Phase II 2017 Department of DefenseNavy

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