Award Data

The broader impact and commercial potential of this Small Business Technology Transfer and Research (STTR) project is a method to control invasive or otherwise unwanted trees and shrubs in an ecologically friendly manner with a biodegradable product. This will reduce the quantity of synthetic herbicides and/or synthetic herbicide adjuvants currently applied to control woody plants. This is especia ...

PROJECT ABSTRACT Short bowel syndromeSBSis a major clinical problem affecting newbornschildren and adultsfor which there is currently no known cureThe disorder results from the functional or anatomic loss of extensive segments of small intestine rendering the intestinal absorptive capacity severely compromisedSBS is clinically defined by malabsorptiondiarrheasteatorrheafluid and electrolyte distur ...

ABSTRACT The goal of this proposal is to develop tumor necrosis factorTNFinhibiting compounds as neuroprotectant drugs for treating Alzheimer s diseaseADCurrent FDA approved AD interventions are symptomatic treatments with limited efficacy which do not affect AD etiology or modify the course of disease progressionThusa critical need exists for a novel AD treatment directed towards AD pathophysiolo ...

Under this subsequent SBIR Phase II proposal, SRICO combines metamaterial narrowband absorbers and proprietary thin film pyroelectric thermal detectors to produce ultra low size, weight, power and cost (SWAP-C) room temperature stand-off chemical sensors. Spectrally and aperture selective metamaterial absorption suppresses blackbody radiation and enables the room temperature pyroelectric sensor to ...

Project Summary AbstractAcute graft versus host diseaseaGVHDis a principal contributor to transplant related mortalityTRMand develops in approximatelyof recipients receiving unrelated donor hematopoietic stem cell transplantationHSCTdespite standard immunosuppressive prophylaxisThusnovel GVHD prophylaxis treatments which successfully attenuate aGVHD and related complications such as infection are ...

Summary AbstractKaposi sarcomaKSis a potentially life threatening consequence of immunosuppression in patients that are infected with human herpes virusHHVMost KS occurs in patients with acquired immunodeficiency syndromeAIDSCurrent KS therapies have limited efficacy and serious off target toxicitiesNavidea has been developingmTc tilmanocepta wholly synthetic molecular construct that binds with ve ...

This proposal will create an open speech signal processing platform. The open computational framework will be used for developing algorithms that will help accelerate acoustic and hearing science research. It will permit researchers to more rapidly and easily test new algorithms with greater control, performance, and ease. Several example systems will be created to show that the platform can be ad ...

Supporting aerospace mission readiness, a system is needed that allows for composite repairs without the current roadblocks imposed by ovens, autoclaves, and expensive tooling. Cornerstone Research Group (CRG), its subsidiary NONA Composites, and the University of Dayton Research Institute (UDRI) presents NASA with the opportunity to obtain a rapid and robust method for on-site composite structura ...

Chemical contamination of spacecraft components as well as thermal and force loading from firing liquid propellant thrusters are critical concerns for in-space propulsion applications. Gas molecular contamination and liquid droplet deposition due to incomplete combustion threaten to damage surface materials, sensitive instruments and optical sensors, and poses major risks for mission success. Liqu ...

In this Phase II STTR project, the proposed collaborative effort between UTC, AFIT, and ULRF represents a crucial step forward for AM. UTC’s unique AM optimization and process control framework, constructed entirely from experimental sensor data collected in-situ, will finally transfer technology from our SLM test bed system to state-of-the-art and commercial-grade systems, including a Concept ...