Award Data

Summary We will create a preclinical quantitative Cancer Imaging and Therapy Platform CITP which will allow one to study cancer biology and optimize pipelines of technologies imaging agents imaging methods targeted nano therapeutics tumor models etc especially for metastatic and invasive cancers Today primary tumor mass es are clinically controlled with surgical drug and radiatio ...

High-energy space radiation from Galactic Cosmic Rays and Solar Particle Events (SPEs) pose significant risks to equipment and astronaut health in NASA missions. Energetic particles from SPEs associated with flares and coronal mass ejections (CMEs) may adversely affect not only beyond-Low-Earth-Orbit missions, but also aircraft avionics, communications, and airline crew/passenger health. It is cru ...

DESCRIPTION provided by applicant This is a resubmission of a Phase I Phase II Fast Track application for the clinical use of MultiStem in patients with acute respiratory distress syndrome ARDS ARDS is defined as acute onset hypoxemia bilateral radiographic pulmonary infiltrates and lack of atrial pressure hypertension A novel and exiting possibility is the use of cells as part of the ther ...

ABSTRACT Although arteriovenous fistulae AVFs are the preferred mode of dialysis vascular access over fail to mature in that they do not develop an adequate blood flow or diameter to support hemodialysis This results in a very significant clinical morbidity and economic cost At a pathogenetic level AVF maturation failure is due to a small vessels b bad non laminar hemodynamic pr ...

An important objective of the NEAMS program is to enable widespread use of the software tools among the industry, academia, and regulatory communities. For solving the problems occurring at various stages of NEAMS simulations, typically there are several possible choices for numerical subroutines. Furthermore, the best method for a numerical problem may also evolve over the course of the simulatio ...

Project Summary Crystallization followed by subsequent structure determination is a major step in understanding the structure function relationship of macromolecules Understanding macromolecule structure has become a key part in the development of new pharmaceuticals and is a major area of NIH research Crystallization however is also the rate limiting step despite technological efforts to a ...

There is an unmet demand for ultra-low-power, ultra-compact and low-cost radios to address emerging sensing and communication needs for military and commercial applications such as IoT/IoE. To overcome the limitations in existing bulky and power hungry radios, we propose a disruptive solution by integration of a nano-scaled THz transceiver, on-chip antenna, and energy harvesting circuits in a form ...

We are proposing to identify an ICME architecture that will enable the multi-scale modeling of additive manufacturing (AM) process at both the component level as well as at the meso-scale level such that the final part quality and performance can be predicted accurately. At the component level, the proposed ICME framework would help in predicting residual stresses, distortion and the necessary sup ...

Kalos Technologies Inc. (Kalos) and Temple University submit together this STTR Phase I proposal entitled Securing the Internet of Things in Tactical Environments to the Air Force in response to solicitation topic AF16-AT10: Securing the Internet of Things. It is the Kalos and Temples effort in the development of hardware-based security, embedded system security, secure communication, and secure I ...

Endpoints in the Internet of Things (IoT) vary considerably in their hardware-software architecture and their functional capability. The IoT marketplace is unlikely to converge on a single or a few dominant endpoint platforms in the near term and potentially even long term future.This creates a major problem and an opportunity for securing IoT endpoints that are being increasingly integrated in cr ...