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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Continuous measurement of cell growth as an optimal tool in drug toxicity testing (Supplement)

    SBC: EnTox Sciences LLC            Topic: NCATS

    DESCRIPTION provided by applicant During the process of screening for drugs with therapeutic potential often times several candidates emerge as prime candidates with similar efficacy and the choice for a lead compound is difficult to make However peopleandapos s lives and billions of dollars may rest on the choice of which compound to bring to clinical investigation and trials Since any lev ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. IRE1 alpha inhibitors for Retinal Degenerative Diseases

    SBC: Optikira, LLC            Topic: N

    DESCRIPTION provided by applicant Approximately Americans suffer from vision loss due to Retinitis Pigmentosa RP Despite significant progress in elucidating the molecular genetics of RP over the past three decades no disease modifying therapies have been approved There is compelling evidence implicating endoplasmic reticulum ER stress in the pathogenesis of various forms of RP e ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. IRE1 alpha inhibitors for type 2 diabetes

    SBC: Optikira, LLC            Topic: 200

    DESCRIPTION provided by applicant The American Diabetes Association has declared type diabetes T D a public health crisis T D begins as a state of compensated insulin resistance frank disease develops when of insulin producing pancreatic islet cells of affected individuals undergo cell death Endoplasmic reticulum ER stress has emerged as a central underlying mechanism that drive ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. STTR Phase I: Mechanical Surface Treatment for High Performance Biodegradable Implants

    SBC: SURFACE INTEGRITY, LLC            Topic: BM

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to shift current practices in bone fracture fixation care from using permanent metal implants to biodegradable metal implants (screws, plates, pins, rods, etc.). A promising biodegradable metal that is gaining widespread attention is magnesium. This project will advance magnesium implant te ...

    STTR Phase I 2015 National Science Foundation
  5. Interface for the collection, analysis, and visualization of simulation performance data

    SBC: Perduco Group, Inc., The            Topic: AF15AT14

    ABSTRACT: To complement capabilities of future autonomous systems, the Air Force requires interoperable tools & methodologies to design, verify, validate, assess & operate human-machine system interactions associated with autonomous and manned systems integration. Often the human performance measures and status of each simulation is reported independently making it challenging to analyze the data. ...

    STTR Phase I 2015 Department of DefenseAir Force
  6. Design, Reconfigure, and Evaluate Autonomous Models in Training

    SBC: TIER 1 PERFORMANCE SOLUTIONS LLC            Topic: AF15AT14

    ABSTRACT: The proliferation of autonomous- and human-machine systems necessitates the creation of new tools for system design and evaluation. Key among these are simulation testbeds that support interactions between multiple warfighters and systems, and methods for creating and integrating intelligent agent models into simulation environments. We see a significant opportunity to advance the state ...

    STTR Phase I 2015 Department of DefenseAir Force
  7. Macromolecule Crystallization Screening Results Analysis

    SBC: iXpressGenes, Inc.            Topic: 100

    DESCRIPTION provided by applicant Crystallization followed by subsequent structure determination is a major step in understanding the structure function relationship of macromolecules Understanding macromolecule structure has become a key part in the development of new pharmaceuticals and is a major area of NIH research Crystallization however is also the rate limiting step despite techno ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Reliable Manufacturing of Scandia-Doped Tungsten Powders for Thermionic Cathodes

    SBC: NGIMAT, LLC            Topic: N15AT010

    In this STTR effort nGimat will partner with the University of Kentucky to develop a new process for manufacturing scandia-doped tungsten powder for use in vacuum tube cathode devices. While a significant amount of research over the last several decades has shown promise for scandate cathode materials, reliable manufacturing processes that enable commercialization of this technology have remained ...

    STTR Phase I 2015 Department of DefenseNavy
  9. Optimized Additive Manufacturing for High Dielectric Strength

    SBC: TETHERS UNLIMITED, INC.            Topic: AF15AT07

    ABSTRACT: To produce high dielectric strength insulator materials, our approach, called Optimized Additive Manufacturing for High Dielectric Strength (OAHDS), will optimize fused filament fabrication (FFF) 3D printing in order to fabricate high density parts. Currently, thermoplastics 3D printed via FFF have dielectric strengths one to three orders of magnitude lower than injection molded parts ma ...

    STTR Phase I 2015 Department of DefenseAir Force
  10. Reverberation Mitigation of Speech

    SBC: MINERVA SYSTEMS & TECHNOLOGIES LLC            Topic: AF15AT17

    ABSTRACT: Speech recognition technology is in wide use today and has been successfully integrated in a number of applications. Most of these applications require a microphone located near the talker. However, when a distant microphone is used where the speaker is at some distance from the microphone as in a hands-free communication, or in a meeting room, there is a major problem with the captured ...

    STTR Phase I 2015 Department of DefenseAir Force
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