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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Long-Duration, Eye-in-the-Sky Monitoring for Airfield Threat Detection

    SBC: DEFENSE RESEARCH ASSOCIATES, INC.            Topic: AF06204

    In today’s Urban-Warfare Command and Control, Intelligence, Surveillance and Reconnaissance (C2ISR) environment, current sensor platforms have a limited operational capability due to power consumption and recharge times. Many times these sensor packages are found to be unsuitable for many battlefield environments due strictly to their endurance limitations. Much of the research done to date has ...

    SBIR Phase II 2010 Department of DefenseAir Force
  2. Affordable Accurate Robot Guidance (AARG)

    SBC: Variation Reduction Solutions Inc            Topic: AF091C001

    The authors establish a novel metrology system capable of determining the pose of a robotically-mounted End of Arm Tool (EOAT) in Six Degrees of Freedom (6-DOF) to a capability better than True Position (TP) 0.010 in. The metrology system consists of low-cost, modular components in the form of motorized gimbals that steer laser beams onto robot-affixed, photosensitive chips typical of those found ...

    SBIR Phase II 2010 Department of DefenseAir Force
  3. Panel Step/Gap Mismatch Measurement

    SBC: PICOMETRIX, LLC            Topic: AF082C001

    In phase II we will develop a prototype TD-THz step/gap mismatch measurement system. This system will be able to measure the sub-surface ground-plane step and gap dimensions on the seams of panels on the F-35 aircraft. In phase I, we demonstrated the ability of the TD-THz method to measure the dimensions of the ground-plane step and gap through otherwise opaque boots and coatings. The first app ...

    SBIR Phase II 2010 Department of DefenseAir Force
  4. Development of a Personalized Medicine Interface for the Safe and Effective Treat

    SBC: PHARMACOGENETICS DIAGNOSTIC LABORATORIES            Topic: NHLBI

    DESCRIPTION (provided by applicant): Improvements in the safety and efficacy of warfarin therapy will result from intelligent application of knowledge derived from inherited characteristics (CYP2C9 and VKORC1) of individual patients, only when this knowledge is applied through a standardized interventional approach. The fundamental pharmacologic influences of CYP2C9 and VKORC1 have been unequi ...

    SBIR Phase II 2010 Department of Health and Human Services
  5. Pre-clinical Development of a Broad Spectrum Antiviral Compound to Treat Human Pa

    SBC: NANOVIR, LLC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The proposal seeks support for the pre-clinical development of broad spectrum compounds for treatment of human papillomavirus (HPV). HPV, the most common sexually-transmitted virus, is the cause of cervical dysplasia and cervical cancer. It has also been implicated in several other hyperproliferative diseases, such as cancers of the mouth and anus, as well as t ...

    STTR Phase II 2010 Department of Health and Human Services
  6. Technologies for the Rapid Curing of Composite Parts (PVCI08-007-1)

    SBC: Vector Composites, Inc.            Topic: AF083C068

    Bismaleimide (BMI) 5250-4 and epoxy 977-3 material systems are used in F-35 aircraft composite components fabricated via autoclave. Alternative out-of-autoclave processes can reduce manufacturing costs by lowering capital and tooling costs and providing faster cure cycles, if properties can be maintained. Feasibility of the Quickstep out-of-autoclave process for 5250-4 and 977-3 material systems h ...

    SBIR Phase II 2010 Department of DefenseAir Force
  7. Refinement of lead compounds to modulate water permeability through AQP4

    SBC: AEROMICS, Inc.            Topic: NINDS

    DESCRIPTION (provided by applicant): Cerebral edema (and its counterpart in the spinal cord) is a major contributor to the damage caused by stroke, traumatic brain injury, traumatic spinal-cord injury, and bacterial meningitis. Stroke alone is the third leading cause of death in the USA and the leading cause of disability. Unfortunately, few treatment options are available for cerebral and spinal- ...

    SBIR Phase II 2010 Department of Health and Human Services
  8. Therapeutic Potential of Ex vivo expanded Human Cord Blood derived CD133+ cells i

    SBC: Arteriocyte, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Critical Limb Ischemia (CLI) is a common problem that often results in major limb amputation. Circulating endothelial progenitor cells likely play a role in the pathogenesis of CLI; the number and function of these cells that are mobilized from the bone marrow are reduced in the elderly and diabetics, groups at high risk for CLI. Allogenic Umbilical Cord Blood ...

    SBIR Phase II 2010 Department of Health and Human Services
  9. Enhanced Propagation of Adult Human Renal Epithelial Cells Allowing for Commercia

    SBC: Innovative Biotherapies, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Renal cell therapy promises to improve the survival and overall health of patients suffering from acute renal failure (ARF), acute tubular necrosis (ATN), multiple organ failure (MOF), sepsis, cardiorenal syndrome (CRS) and end stage renal disease (ESRD). To this end, therapeutic biological devices addressing the neglected physiologic component of renal replace ...

    SBIR Phase II 2010 Department of Health and Human Services
  10. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health

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