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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. NANOMETAL-POLYMER HYBRIDS FOR COMPLEX HIGH TEMPERATURE AEROSPACE COMPONENTS

    SBC: Integran Technologies U.S.A. Inc.            Topic: DLA10001

    Integran USA (Pittsburgh, PA) is pleased to provide this proposal in response to the Small Business Innovation Research (SBIR) Request for Proposal (RFP) DLA10-001)"Advanced Technologies for Discrete-Parts Manufacturing"to develop a manufacturing process for allowing the further use of polymers in high temperature aerospace

    SBIR Phase I 2011 Department of DefenseDefense Logistics Agency
  2. Compact Solid State Deep Ultraviolet (UV) laser for Raman detection of CB agents

    SBC: SNAKE CREEK LASERS LLC            Topic: CBD11105

    This topic addresses the need for compact efficient solid-state deep ultraviolet (UV) lasers operating in the wavelength range of 220-250 nm, for use in Raman systems for chemical and biological detection. The laser to be developed would also be very useful in the detection of explosives. We propose to develop an efficient 946 Q-switched nm laser system that is efficiently quadrupled to 236.5 nm. ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  3. Compact Piezoelectric High Intensity Sound Source

    SBC: Omega Piezo Technologies            Topic: CBD11108

    There is a market need for high intensity sound sources that can operate for long durations over wide temperature ranges and in environments with dust and humidity exposure. Piezoelectric sound sources offer many advantages over compression drivers in these applications. They can be small and lightweight, have low power consumption, operate in narrow frequency bands, and can achieve a high sound p ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  4. Robust Piezoelectric Sound Source with Helmholtz Acoustic Amplification

    SBC: KCF TECHNOLOGIES, INC.            Topic: CBD11108

    KCF Technologies proposes to develop a robust and efficient sound generator for separation/isolation of aerosols. The critical limitations in the performance of conventional piezoelectric sound generators include degradation in performance over long periods of operation, poor electro-acoustic efficiencies at high amplitude drive levels, and large tolerances in their acoustic performance. These pro ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  5. Microfluidic High-throughput Platform for Determining of Kinetic Constants of Enzyme Variants

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10107

    Molecular biology techniques allow generating combinatorial libraries of large number of enzyme variants. However, there is currently no technology available for screening the enzyme libraries for identifying variants with improved activity for the substrate. We propose to develop a novel, microfluidic, high-throughput platform for determining kinetic constants of enzyme variants and identifying v ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  6. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10103

    Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  7. In vitro Models Suitable for High-throughput Screening of Drug Toxicities in Human Tissues

    SBC: Nico Technologies Corp.            Topic: CBD10103

    The drug R&D cycle is long and very expensive. In many ways, this status quo can no longer be sustained. One of the reasons for such great cost is that the vast majority of drug candidates are screened out at the stages of animal and human trials. More efficient methods of testing of drugs at the stage of ex-vivo studies, which are substantially less expensive than animal and human testing cyc ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  8. AC Impedance Sensor for Collective Protection Filter Residual Life Indicator

    SBC: GUILD ASSOCIATES INC            Topic: CBD10106

    Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  9. An automated, high throughput, resin-free device for large scale protein purification

    SBC: CFD RESEARCH CORPORATION            Topic: CBD12102

    Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  10. Rapid Sample Transport in Austere Environments

    SBC: PIASECKI AIRCRAFT CORP            Topic: CBD12108

    Piasecki Aircraft proposes to meet the challenge of delivering a biological or chemical sample maintained at less than -20 deg Celcius over a range of up to 1000 miles with a precision landing with a portable unmanned aerial system capable of a vertical takeoff, cruise flight range typical of a fixed wing platform, and able to perform a precision landing. The system consists of a lifting quadrotor ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
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