Award Data

Project Summary Environmental risk factors are attributable toof the chronic respiratory disease burden in the U Sand toof the burden from other non communicable diseasese gcancercardiovascular diseaseand diabetesExposure to environmental risk factors occurs through various forms of water and air pollutionwith a smaller attribution to sources like noiseradiationand physical hazardsMuch of this exp ...

ABSTRACTSubstance use disordersSUDsincluding opioid use disorderscontinue to be one of the most serious public health issues in the USleading to negative physical and mental health problemsfamily disruptionand premature deathAfrican Americans with drug use histories that are under criminal justice supervision are particularly vulnerable to experiencing the negative consequences associated with SUD ...

Project Summary While studies support the efficacy of comprehensiveschool wide interventions in reducing bullyingthese types of programs can require significant time and financial resources for implementationresulting in barriers to providing school based bullying preventionespecially in low income and rural communitiesAdditionallyalthough training bystanders to act asdefenderson behalf of targets ...

Project Summary/Abstract Objective: This project aims to elevate electron beam therapy (EBT) technology, which provides effective radiation treatment for superficial cancers (depthandlt;6 cm), to that of other external beam radiotherapies (XRT), e.g. x-rays and protons, by bringing electron intensity modulation into the clinic. Challenge: Approximately 10% of radiotherapy patients (173,000 in U ...

The broader/commercial impact of this SBIR Phase I project addresses the important unmet clinical need of enabling interventional radiologists to prevent pneumothorax (collapsed lung) during transthoracic lung biopsies. Annually, over 1.2 million transthoracic lung biopsies are performed worldwide for lung cancer diagnosis (400,000 in the US). Pneumothorax (PTX), a collapsed lung, is the most comm ...

Preventing Vascular Complications in Type 1 Diabetes: Muscle Metabolic Monitoring Abstract Measurements of muscle metabolism and blood flow using near infrared spectroscopy (NIRS) have progressively increased, as has the number of companies selling NIRS-based devices. This technology represents the present and future modality for non-invasively characterizing normal and abnormal muscle physiology ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will result from a focus on families with low socioeconomic status (SES), in whom adverse childhood experiences (ACE) and opioid use disorder (OUD) are common. Children of parents with OUD have higher incidences of ACE due to neglect, physical abuse, or domestic violence. ACE have life-long ad ...

The broader impact/commercial potential of this SBIR Phase I project is to develop a desalination system powered by solar energy. Water is used for lithium and rare metal mining, requiring energy-efficient water treatment to produce fresh water and concentrated brines. This type of water treatment in mineral recovery systems can yield valuable critical materials as byproducts. Many lithium and rar ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to reduce injuries and costs due to overexertion and heat strain in firefighting through a real-time, biometric monitoring system and accompanying analysis tools. This system collects each firefighter's vital signs and sends the data to authorized commanders for real-time strategic decisio ...

Project Summary Stroke is the 5th leading cause of death and number one cause of adult disability in the United States. The primary goal of acute ischemic stroke (AIS) treatment is quickly restoring blood perfusion. However, studies have shown that this return of blood flow, while necessary, can also cause damage to local tissue leading to poor patient outcomes. Therapeutic hypothermia (TH) has be ...