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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 4095 results
  1. Lentiviral-MGMT gene transfer into hematopoietic stem cells

    SBC: LENTIGEN CORPORATION            Topic: NCI

    DESCRIPTION (provided by applicant): Therapeutic stem cell gene transfer relies on long-term gene expression achieved by integration of new DNA into the cellular genome. Current clinical trials featuring oncoretroviruses have encountered a number of roadblocks that include low levels of gene transfer, poor expression, and a recognized preferential insertion near promoter regions that increases the ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. A SAFE AND COMPACT NEONATE TO ADULT NEUROIMAGING MRI SYSTEM

    SBC: ADVANCED IMAGING RESEARCH, INC.            Topic: 101

    NIH SBIR PA-18-871 w/o Clinical Trials A Safe and Compact Neonate to Adult Neuroimaging MRI System The intriguing human brain is the most imaged end-organ non-invasively, without ionizing radiation using magnetic resonance imaging (MRI). High spatial resolution brain MRI is an established diagnostic tool to assess injury mechanisms affecting newborn growth and the adult human connectome. To predic ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Topic 369: DRUG DELIVERY SYSTEM TO SAVE HEARING DURING PEDIATRIC CHEMOTHERAPY REGIMENS

    SBC: Otomagnetics, Inc.            Topic: NCI

    Our company has invented a magnetic drug delivery device that we intend to develop to enable prevention of a major side effect of chemotherapy in children. Cisplatin and carboplatin chemotherapy regimens can lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed on-label as a dose limiting toxicity. Hearing loss in kids has a dramatic impact on the ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. GENETIC CYTOLOGY FOR SURVEILLANCE OF RECURRENT BLADDER CANCER

    SBC: PAPGENE, INC.            Topic: NCI

    This proposal details the development of UroSeqS as a genetic cytology test to extend the utility of routinely collected urine specimens to the detection of recurrent bladder cancer UroSeqS is a genetic cytology assay that achieves sensitivity and specificity through identifying DNA mutations causative of cancer from routinely collected clinical specimens An innovative approach is used toanalyz ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a TRAIL-based therapy for alcohol related chronic pancreatitis

    SBC: Theraly Fibrosis, Inc            Topic: 150

    Project Summary The goal of this project is to advance a new treatmentTLYas the firstdisease modifying agent that addresses two critical physiological and pathological features of chronic pancreatitisCPfibrosis and severe painCP is a progressive inflammatory disorder of the pancreaspredominantly caused by alcohol abuseCP leads to pancreatic fibrosis and eventually irreversible destruction of the p ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. A single dose long-acting non-addictive polymer conjugate formulation of buprenorphine that provides immediate and prolonged analgesia for post-operative pain

    SBC: SERINA THERAPEUTICS INC            Topic: NINDS

    PAProject Summary Abstract SERis a long acting polymer pro drug of buprenorphine that is being developed to treat postoperative pain following major surgeries such as bunionectomyabdominoplastythoracotomy and knee and hip surgerySERhas no biological activity by itselfbut when administered in vivo by subcutaneous injection it enters the vascular compartment where a plasma esterasebutyrylcholinester ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. TOPIC 363- Caregiver Buddy: Leveraging Standards to Help Cancer Caregivers and Clinicians

    SBC: CARE PROGRESS LLC            Topic: NCI

    This research project seeks to create innovative software that aids cancer patient caregivers,by improving their ability to access patient information, communicate with clinicians, and provide peer support. We seek to leverage the insights of stakeholders and subject matter experts as well as industry standards to enhance a caregiver facing SmartPhone app and related software developed in Phase I ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Structurally Diverse GABA-A?5 Positive Allosteric Modulators for Treatment of MCI due to AD

    SBC: Agenebio, Inc.            Topic: NIA

    The overall objective of this SBIR application is to develop a potentselective and orally active GABA APositive Allosteric ModulatorPAMfor the treatment of Mild Cognitive Impairment due to Alzheimer s DiseaseMCI due to ADThere are currently no approved therapeutics for this indication making this an area of extremely high unmet needThere is strong support from preclinical AD models and human patie ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Tumor-toxic CD47 mAb therapy for leukemia: a proof of concept study

    SBC: SIMMERSION LLC            Topic: NIAAA

    DESCRIPTION (provided by applicant): The goal of this Phase I/Phase II Fast-Track application is to develop and evaluate a simulation-based product for training student affairs staff (e.g., resident assistants [RAs], Greek life staff, campus and housing security, student conduct staff, and academic advisors) to assess and provide appropriate intervention to students who engage in risky drinking be ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Portable Ankle Robotics to Reverse Foot Drop After Stroke.

    SBC: NEXTSTEP ROBOTICS, INC.            Topic: NINDS

    This proposal finalizes the design of a portable ankle robot as a therapeutic device to reverse foot drop and restore safer independent walking after stroke, then conducts a rigorous randomized clinical trial to establish clinical proof for this new market application. Currently, there are no therapeutic solutions for foot-drop, only assistive devices (braces, canes, electrical stimulation) that d ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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