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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. HUCBC modulation of Alzheimer's-like pathology and behavioral changes

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): In the past years, we have shown that human umbilical cord blood cells (HUCBC, U-CORD- CELL ) provide cognitive recovery in animal models of neurodegenerative disease. Infusion of HUCBC resulted in reduced infarct volume as well as in rescue of behavioral benefits in an animal model of stroke. We further showed that HUCBC infusion proved to be beneficial in ani ...

    STTR Phase II 2010 Department of Health and Human Services
  2. A Home Exercise Program (DVD) for Women with Infants and Young Children

    SBC: KLEIN BUENDEL, INC            Topic: NIDA

    DESCRIPTION (provided by applicant): Becoming a mother is a significant transition in a woman's life. This transition can precipitate major changes in health behaviors, like physical activity. Once a woman has a child she is much less likely to participate in regular, moderate to vigorous physical activity compared to women without children. Thus, new mothers are at risk for future weight gain and ...

    STTR Phase II 2010 Department of Health and Human Services
  3. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Electro Optic Avionic Advanced Guidance, Navigation and Control (GNC) Algorithm Development to Enhance the Lethality of Interceptors Against Maneuveri

    SBC: Polaris Sensor Technologies, Inc.            Topic: MDA08T003

    This Phase II effort will further develop a technique to improve current seeker discrimination and tracking capabilities using a unique particle filter algorithm (PFA) approach. The advancement represents a significant upgrade to current and future seekers facing advanced threats in stressing environments. Quantifiable improvements over many facets of the current approach have been realized during ...

    STTR Phase II 2010 Department of DefenseMissile Defense Agency
  5. Multipurpose reversible terminators

    SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC            Topic: NHGRI

    DESCRIPTION (provided by applicant): This Phase 2 STTR application will allow the Foundation for Applied Molecular Evolution (FfAME) to complete its transfer of technology to Firebird Biomolecular Sciences LLC, allowing Firebird to commercialize nucleoside triphosphates where the 3'-OH groups are blocked by a 3'-ONH2 group. Triphosphates having this modification are accepted by DNA polymerases and ...

    STTR Phase II 2010 Department of Health and Human Services
  6. Targeting glioblastoma stem-like cells with custom-designed viral vectors

    SBC: Lacerta Therapeutics, Inc.            Topic: 102

    GlioblastomaGBMis the most lethal form of adult brain cancers with a median survival of andltmonths despite aggressive standard chemoradiationGBM are formed by GBM stem like cellsGSCsa major contributor to tumor recurrence and a natural focus for therapeutic developmentThere are two main reasons responsible for treatment failurehigh intraand inter tumor cellular and molecular heterogeneity with mu ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Low-cost, Time-resolved Chemical Characterization of Atmospheric Aerosols

    SBC: Aerosol Devices Inc.            Topic: 23b

    The composition of atmospheric particulate matter (“aerosols”) strongly influences health and environmental impacts, but there exist few time-resolved, long-term records of particle-phase chemical composition due to lack of appropriate monitoring tools. Needed is an instrument that is robust, easy-to-operate, with automated calibrations and data reduction, to provide operationally-inexpensive ...

    STTR Phase II 2019 Department of Energy
  8. Internet-based Fidelity Enhancement of MTFC

    SBC: Tfc Consultants, Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): The proposed project builds upon Phase I proof of concept efforts wherein the basic foundational components of an Internet-based Treatment Fidelity Monitoring System, the ITFMS, were created to assist MTFC consultants and implementing agencies to improve clinical outcomes by moving more efficiently towards and maintaining fidelity of program implementation. I ...

    STTR Phase II 2010 Department of Health and Human Services
  9. Flow Battery Structures to Improve Performance and Reduce Manufacturing Cost

    SBC: Faraday Technology, Inc.            Topic: 21d

    Redox flow batteries are a promising technology for electrical energy storage for renewable energy sources; however traditional redox flow batteries are limited in their use due to non-uniform pressure drops and mass transfer limitations, as well as high manufacturing costs related to the felt material costs for the electrode and component alignment challenges during manufacturing.General Statemen ...

    STTR Phase II 2013 Department of Energy
  10. Developing a Small Peptide to Control Autoimmune Inflammation In Type 1 Diabetes

    SBC: Op-T-Mune, Inc            Topic: NIAID

    TypeDiabetesT Daffects an ever growing populationWhile this disease typically has been associated with juvenilesthe disease in adult populations is rapidly increasingThe defining clinical component is insulin losswhich occurs because of sustained inflammation in the isletsAt present there is no means to prevent or reverse insulin lossA major inflammatory pathway in T D that contributes to insulin ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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