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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Metal Digital Direct Manufacturing (MDDM) for Close-Out of Combustion Chambers and Nozzle Fabrications

    SBC: Keystone Synergistic Enterprises, LLC            Topic: T12

    This NASA sponsored STTR project will investigate methods for close-out of large, liquid rocket engine, nickel or stainless steel nozzle, coolant channels utilizing robotic laser and pulsed-arc additive manufacturing (AM)methods. Structural jacket to coolant channel land area interface strength will be quantified and metallurgical characterization completed.Process optimizations will be conducted ...

    STTR Phase II 2019 National Aeronautics and Space Administration
  2. Highly Sensitive Flash LADAR Camera

    SBC: VOXTEL, INC.            Topic: T9

    To address the urgent need for 3D flash-lidar technology for landing on solar system bodies and for spacecraft rendezvous and docking with satellites, an effort is proposed to fabricate, characterize, and test a versatile, high-sensitivity InGaAs APD 3D flash lidar and to advance the technology-readiness level (TRL) of lidar technologies suitable for NASA mission requirements. Leveraging an existi ...

    STTR Phase II 2019 National Aeronautics and Space Administration
  3. Biosensor and Eyedrop Bottle Technologies for Glaucoma Adherence Monitoring

    SBC: Toromedes, Inc            Topic: NEI

    Project SummaryNon adherence with prescribed systemic drugs leads to poor outcomes and increases the cost of healthcareGlaucomathe leading cause of irreversible blindnessaffects more thanmillion people worldwideLowering intraocular pressurethe only proven method of delaying both the development and progression of glaucomais typically done with topical administration of eye dropswhich has notorious ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Targeting neurotoxic alpha-synuclein aggregates for Parkinson's disease therapy.

    SBC: Vova Ida, LLC            Topic: 999

    SUMMARYParkinsonandapos s diseasePDis the second most prevalent neurodegenerative disorder after Alzheimerandapos s diseaseADaffecting more thanmillion people in the United StatesBecause age is the major risk factorthe prevalence of both diseases is steadily increasing as our population agesPD belongs to the group of protein misfolding neurodegenerative diseases that are due to the misfolding and ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Targeting lipid rafts for treatment of migraine

    SBC: RAFT PHARMACEUTICALS LLC            Topic: NINDS

    PROJECT SUMMARY Migraine is a highly prevalent condition with an extraordinarily negative impact on quality of life and represents a heavy socioeconomic burden to the societyprimarily because of decreased working efficiency and workdays lostManagement of migraine has become increasingly pharmacological during recent yearsWhile several therapeutic options existmost of the prophylactic drugs current ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Novel monoclonal antibody for single dose treatment of acute CNS injury

    SBC: OncoSynergy, Inc.            Topic: NINDS

    PROJECT SUMMARY Traumatic brain injuryTBIrepresents a significant societal and economic impactTo datethere are no FDAapproved pharmacotherapies to prevent or reverse TBIThe standard of care in an emergency setting focuses first on stabilizing the patient and secondly on management of cerebral hemodynamicsThe patient may undergo surgery to remove hematomasrepair skull fracturesand relieve intracran ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Pre-clinical evaluation of DT-001, a small molecule antagonist of MD2-TLR4 for utility in the treatment of pain.

    SBC: Douleur Therapeutics Inc            Topic: NINDS

    Project Summary AbstractUpwards ofmillion individuals are afflicted by chronic pain in the US alonewithmillion of these individuals suffering from neuropathic painOn a global scalechronic pain affectsbillion individualswithwho endure lower back painFrom a clinical perspectivethe International Association for the Study of Pain approximates thatinpatients present with painand on an annual basisinpat ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Soft Robotic Manipulators with Enhanced Perception using Multimodal Sensory Skins

    SBC: Other Lab Inc.            Topic: T11

    Otherlab and the Faboratory propose that a key component of future NASA robot technology will benbsp;continuum joint-based fluidic actuation, valuable for its light weight, low packing volume, inherent shock amp; vibration isolation, and ability to interact safely with unstructured environments and near humans.nbsp;Over the course of our Phase I amp; Phase II projects we have developed such a nove ...

    STTR Phase II 2019 National Aeronautics and Space Administration
  9. A Novel Two-in-One Approach to Administer Surfactant and Provide Airway Support to VLBW Infants

    SBC: BB MEDICAL SURGICAL, INC.            Topic: NICHD

    PROJECT SUMMARYABSTRACT Every yearvery low birth weightVLBWandltginfants are born in the U SThe use of surfactant dramatically decreases morbidity and mortality due to respiratory distress syndromeRDSin VLBW infantsCurrent standards for surfactant administration require the infant to be intubatedso that surfactant can be delivered to the trachea and lungsIntubating a VLBW infant is challenging and ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. LystaMab Immunotherapy to Inhibit Pericardial Adhesions

    SBC: Lyst Therapeutics LLC            Topic: NHLBI

    SUMMARY Despite significant advances in the surgical and medical management of congenital heart diseasecongenital cardiac anomalies remain a leading cause of death in the newborn periodMost severe forms of congenital heart disease require multiplestaged surgical interventionsA significant source of the heightened morbidity and mortality associated with these operations is the development of cardia ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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