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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. HUCBC modulation of Alzheimer's-like pathology and behavioral changes

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): In the past years, we have shown that human umbilical cord blood cells (HUCBC, U-CORD- CELL ) provide cognitive recovery in animal models of neurodegenerative disease. Infusion of HUCBC resulted in reduced infarct volume as well as in rescue of behavioral benefits in an animal model of stroke. We further showed that HUCBC infusion proved to be beneficial in ani ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Targeting glioblastoma stem-like cells with custom-designed viral vectors

    SBC: Lacerta Therapeutics, Inc.            Topic: 102

    Glioblastoma (GBM) is the most lethal form of adult brain cancers with a median survival of andlt;15 months despite aggressive standard chemoradiation. GBM are formed by GBM stem-like cells (GSCs) - a major contributor to tumor recurrence and a natural focus for therapeutic development. There are two main reasons responsible for treatment failure: 1) high intra- and inter-tumor cellular and molecu ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. High Throughput Testing of Additive Manufacturing

    SBC: MRL MATERIALS RESOURCES LLC            Topic: N18AT028

    Additive manufacturing is a disruptive new manufacturing paradigm that hold tremendous potential for creation of novel designs and introduction of novel new alloy systems. However, much of this potential remains unrealized due to a lack of robust material properties databases. Accurate calibration of materials models and robust part qualification and certification regimes both will require massive ...

    STTR Phase II 2019 Department of DefenseNavy
  4. Information-based Norms on Flow, Operations and Traffic Over Networks (INFOTON)

    SBC: ISEA TEK, LLC            Topic: N18AT027

    The Internet of Things (IoT) connects people, data, and "things" (e.g., software, sensors, platforms), facilitating the translation of information into actions. Although naval platforms’ networks and communication suites have evolved significantly in the past few years to support such required connectivity, one of the greatest technical challenges still facing the military community is the proce ...

    STTR Phase II 2019 Department of DefenseNavy
  5. A Home Exercise Program (DVD) for Women with Infants and Young Children

    SBC: KLEIN BUENDEL, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): Becoming a mother is a significant transition in a woman's life. This transition can precipitate major changes in health behaviors, like physical activity. Once a woman has a child she is much less likely to participate in regular, moderate to vigorous physical activity compared to women without children. Thus, new mothers are at risk for future weight gain and ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Developing a Small Peptide to Control Autoimmune Inflammation In Type 1 Diabetes

    SBC: Op-T-Mune, Inc            Topic: NIAID

    Type 1 Diabetes (T1D) affects an ever growing population. While this disease typically has been associated with juveniles, the disease in adult populations is rapidly increasing. The defining clinical component is insulin loss, which occurs because of sustained inflammation in the islets. At present there is no means to prevent or reverse insulin loss. A major inflammatory pathway in T1D that cont ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Repair of Materials Degradation in Light Water Reactor Components

    SBC: UES SERVICES INC            Topic: 08c

    Corrosion induced degradation of material components in the harsh environment of light water reactor can impact reactor reliability, availability, safe operation and eventually life. A possible remedy could be to replace the replaceable components at appropriate moments which may not be economically favorable. Thus there is a need to develop technologies to repair degraded materials. STATEMENT OF ...

    STTR Phase II 2016 Department of Energy
  9. Low Cost Magnetic Sensor for Mine Neutralizer Identification and Charge Placement

    SBC: QUSPIN INC.            Topic: N17AT013

    Optically pumped magnetometers provide very high performance but they cost tens of thousands of dollars, and they are large and power hungry. Recently we successfully developed and commercialized laser pumped magnetometers with size, weight and power consumption that is an order of magnitude below current state-of-the-art without sacrificing performance. In this project, the focus will be on produ ...

    STTR Phase II 2019 Department of DefenseNavy
  10. Automated Intestinal Electrical Stimulation for Diabetes

    SBC: TRANSTIMULATION RESEARCH INC            Topic: 200

    Diabetes affects more than 9% of Americans and costs over $300 billion in 2017 in USA. Medical therapies have limitations in treating diabetic patients with obesity due their common side effects of weight gain. Bariatric surgery has been proposed for treating diabetic patients with promising outcomes. In this project, we propose a novel method of intestinal electrical stimulation (IES) for treatin ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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