Award Data

The objective of this proposal is to examine the feasibility of defining and measuring key dimensions of an urban system to include its essential functions and networks, and whether they can be modelled in a computational framework for assessing robustness and resilience of DUTs (and their tipping points) under conditions of volatility and stress. This proposal will conduct a comprehensive review ...

Genome-scale predictable cellular design and engineering of biomanufacturing systems is the overarching a goal of DARPA's Living Foundry thrust and, if realized, will enable rapid engineering of living biosystems for a broad range of applications in biotechnology and pharmacology. However, constructing living cells with designed genome is not fully automated and is severely limited by inhere ...

Acclimatization is the long-term adjustment that humans experience when exposed for weeks or months to high altitude. Acclimatization is important in this context because a warfighter who is acclimatized to high altitude is immune to high altitude illness, has superior work capacity, and has cognitive function approaching that found at sea level. In other words, the acclimatized warfighter is opti ...

Federal Aviation Administration Advisory Circular 20-107B provides guidance on the achievement of compliance with Title 14 of the Code of Federal Regulations regarding airworthiness type certification requirements for composite aircraft structures necessi

Pressure gain combustion has the potential to significantly improve the specific fuel consumption for gas turbine engines by realizing a pressure rise through the combustor as opposed to a pressure drop. One drawback to this form of combustion is the cycl

We propose to develop a computational model of leadership designed to capture complex variables including cultural differences in leadership requirements along with task differences, primarily ill-defined goals, which pose leadership challenges. Rather than avoiding these kinds of complexity and developing a computational model that is unlikely to scale up, we believe there is more to be gained b ...

In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

Opportunity: Guayule, a US native plant, is the only alternate rubber crop with an established, mechanized, agronomic system. Problem: Low rubber yields and lack of effective resin and bagasse coproduct valorization, have prevented widespread adoption by American farmers and processors. Rubber is only made when the cytoplasmic monomer pool (isopentenyl-pyrophosphate; IPP) is larger than that requi ...

The objective of this proposal is to develop instrumentation and algorithms for acquiring facial features for facial recognition in low- and no-light conditions.We will use cross-spectrum matching by exploiting infrared polarimetric imagery which tends to show features that match more closely visible imagery than conventional infrared.In addition to thermal infrared, we will also test subjects in ...