Award Data

We propose to investigate, in collaboration with MGH Voice Center and Altec, Inc., application of surface electromyography (sEMG) to assessing cognitive workload, strain, and overload. Specifically, sEMG sensors placed on the face and neck will detect emotional/motor responses to workload strain. The proposed effort will build on the substantial sEMG experience of our partner, MGH (including resea ...

Nanoscale, material sensitive, imaging techniques are critical for progress in many disciplines as we learn to master science and technology at the smallest dimensions — on the nanometer to atomic-scale. However, progress in both science and technology is becoming increasingly limited by the constraints of current imaging techniques and metrologies. Fortunately, by combining coherent extreme UV ...

The variational two-electron reduced-density matrix (v2RDM) method provides an effective framework for computer modeling of the electronic structure of complex molecules and materials that exhibit strong correlation effects. In Phase I and Phase II of this STTR we have demonstrated that the GPU-accelerated implementation of the v2RDM-based complete active space self-consistent field (v2RDM-CASSCF) ...

Pulse voltammetry techniques, coupled with model-based analysis tools, provide a number of advantages for quantitative analysis of electrochemically active materials that govern the performance of batteries and fuel cells. In prior Phase I and II research, CFD Research developed and validated computational models in software that reads voltammogram data from laboratory instruments; predicts the re ...

Methods for interconversion between cell types (cellular reprogramming) are currently discovered through resource intensive trial and error. Experiments may test a multitude of transcription factors to identify correct combinations that influence cell fate. In addition, reprogramming approaches commonly use stem cell intermediates such as induced pluripotent stem cells (iPSCs), which are generated ...

Environment-security researchers and practitioners must overcome several technical challenges in the course of their efforts. In the absence of an open-community platform, each researcher or institution compiles and curates their own data repositories, analytical tools, and computational environments. This results in significant duplication of effort, limits the replication and validation of resea ...

Opportunity: Guayule, a US native plant, is the only alternate rubber crop with an established, mechanized, agronomic system. Problem: Low rubber yields and lack of effective resin and bagasse coproduct valorization, have prevented widespread adoption by American farmers and processors. Rubber is only made when the cytoplasmic monomer pool (isopentenyl-pyrophosphate; IPP) is larger than that requi ...

Deposition of highly conductive, continuous thin film metals has proven to be a significant challenge. There are several techniques that allow deposition of these metals, but their application is limited to planar surfaces and only offer complete line of sight deposition. During a recent Phase I STTR project, Summit Information Solutions, Inc. (Summit), in partnership with University of Alabama in ...

On-site activated decontaminants will revolutionize chemical and biological decon because the activated solution is produced on demand, without the limitations of traditional pre-made mixtures. TDAs system uses electrical activation to convert battery power into reactive chemicals that quickly destroy chemical and biological warfare agents. Prior to activation, the decontaminant mixture can be saf ...

Our nation’s warfighters require advanced armor to give them the best protection while allowing mobility to perform their missions. This proposal will develop two powerful tools to aid future body armor advancements. First, this research program will develop a statistical analysis software that will predict likelihood of impacts based on defined attack scenarios (i.e. rifle, distance and firing ...