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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Human Performance Optimization

    SBC: HVMN Inc.            Topic: SOCOM17C001

    During altitude-induced hypoxia, operator cognitive and physical capacity degrades, compromising individual and team performance. Cognitive degradation is linked to falling brain energy levels, increased reliance on anaerobic energy production and lactate accumulation. Ketones are the evolutionary alternative substrate to glucose for brain metabolic requirements; previous studies demonstrated that ...

    STTR Phase II 2019 Department of DefenseSpecial Operations Command
  2. Rapid Immunodiagnosis of Drug-Resistant Bacterial Pathogens

    SBC: SILVER LAKE RESEARCH CORPORATION            Topic: NIAID

    PROJECT SUMMARY ABSTRACT This proposal describes Phase II of the development of a rapid immunoassay test kit for the determination oflactam antibiotic resistanceto be used as a point of care diagnostic test for urinary tract infectionsTodayantibiotics for UTI are prescribed empiricallywith no diagnostics available to clinicians to avoid treating resistant infections with the very drug to which the ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Preclinical Testing of a Novel Flow Diverting Stent for Treating Intracranial Aneurysms

    SBC: NeuroSigma, Inc.            Topic: 101

    DESCRIPTIONprovided by applicantThe purpose of this project is to develop an improvedminimally invasive treatment for intracranial aneurysmsIntracranial aneurysms are spherical outpouchings of blood vessels in the head that result from weakness in the vessel wallUnruptured aneurysms are present in approximatelyof the general populationand rupture can be devastating with a high morbidity and mortal ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Preclinical Development of OCF001 for Treatment of Yeast Infections

    SBC: Sano Chemicals, Inc.            Topic: NIAID

    Project Summary Occidiofungins (A-D) are cyclic nonribosomally synthesized antifungal peptides with submicromolar fungicidal activity against a broad spectrum of fungi. Optimization of the production and isolation of occidiofungins from liquid cultures has been performed. The production and isolation of predominantly one analog, called occidiofungin B (OCF001), supports its commercial development ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. HUCBC modulation of Alzheimer's-like pathology and behavioral changes

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): In the past years, we have shown that human umbilical cord blood cells (HUCBC, U-CORD- CELL ) provide cognitive recovery in animal models of neurodegenerative disease. Infusion of HUCBC resulted in reduced infarct volume as well as in rescue of behavioral benefits in an animal model of stroke. We further showed that HUCBC infusion proved to be beneficial in ani ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Detect and Avoid Certification Environment for Unmanned Air Vehicles (UAVs)

    SBC: RDRTEC INCORPORATED            Topic: N18AT007

    The objective of this project is to develop a comprehensive suite of tools, called the DAA Radar Software Suite and Simulation (DAA-RSSS), that supports future Navy procurement and certification of non-cooperative sensor technologies for Detect And Avoid (DAA) as well as develop plans to support EO/IR sensors as the non-cooperative sensor as informed by FAA activities in developing Minimum Operati ...

    STTR Phase II 2019 Department of DefenseNavy
  7. Multiple Images Spatial Turbulence Imager (MISTI)

    SBC: POLARIS SENSOR TECHNOLOGIES INC            Topic: AF071340

    Because of the maneuvering capabilities of adversaries’ new hypersonic weapons, defensive missiles must fly in very demanding flight regimes, and intercept maneuvers place stringent requirements on interceptor seeker systems. Successfully completing the hit-to-kill end game requires the seeker can either compensate for or perform despite the thermal and optical effects that cause the seeker to m ...

    STTR Phase II 2020 Department of DefenseMissile Defense Agency
  8. Targeting glioblastoma stem-like cells with custom-designed viral vectors

    SBC: Lacerta Therapeutics, Inc.            Topic: 102

    Glioblastoma (GBM) is the most lethal form of adult brain cancers with a median survival of andlt;15 months despite aggressive standard chemoradiation. GBM are formed by GBM stem-like cells (GSCs) - a major contributor to tumor recurrence and a natural focus for therapeutic development. There are two main reasons responsible for treatment failure: 1) high intra- and inter-tumor cellular and molecu ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Protocol Feature Identification and Removal

    SBC: P & J ROBINSON CORP            Topic: N18AT018

    Protocols used for communication suffer bloat from a variety of sources, such as support for legacy features or rarely used (and unnecessary) functionality. Traditionally, the Navy subscribes to a blanket adoption of a standard protocol "as is". Unnecessary features are active and can be accessed by both internal and external systems creating security vulnerabilities. PJR Corporation's (PJR's) Pha ...

    STTR Phase II 2019 Department of DefenseNavy
  10. Data Analytics and Machine Learning Toolkit to Accelerate Materials Design and Processing Development

    SBC: CFD RESEARCH CORPORATION            Topic: N19AT020

    The US Navy has identified refractory high entropy alloys (RHEAs) and metal additive manufacturing (AM) as enabling technologies to meet performance and sustainability targets for shipboard and aircraft systems. Key challenges include designing RHEAs and optimizing metal AM to achieve desired material properties for Navy propulsion applications. Developing materials and processes via traditional e ...

    STTR Phase II 2020 Department of DefenseNavy
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