Award Data

Summary AbstractYouth under ageinvolved in the criminal justice system are disproportionately minorities and affected by substance abusemental illnessand HIV STIMost young offenders are released on community supervision without the STImental healthor substance use screeningdiagnosisand treatment afforded detained youthdespite similar rates of risk behaviorTheir long term trajectory is poorthe cost ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to accelerate product development and domestic manufacturing by introducing a new method of fabricating products in a geographically distributed manner. The United States enjoys global prominence as a hub for cutting-edge research and creative design. However, investment has migrated overseas where ...

The broader impact/commercial potential of this SBIR Phase I project is to develop a desalination system powered by solar energy. Water is used for lithium and rare metal mining, requiring energy-efficient water treatment to produce fresh water and concentrated brines. This type of water treatment in mineral recovery systems can yield valuable critical materials as byproducts. Many lithium and rar ...

Project Summary The successful management of chronic pain is inadequate in many patients and has contributed to the abuse of and addiction to opioidsa continuing major public health crisis in the United States and worldwideThe development of non addictive pain therapeutics can help counter opioid addiction and benefit patientsincluding those who suffer from neuropathic painand in particular diabet ...

PAProject Summary Abstract SERis a long acting polymer pro drug of buprenorphine that is being developed to treat postoperative pain following major surgeries such as bunionectomyabdominoplastythoracotomy and knee and hip surgerySERhas no biological activity by itselfbut when administered in vivo by subcutaneous injection it enters the vascular compartment where a plasma esterasebutyrylcholinester ...

ABSTRACT SignificanceThere are overmillion people with insulin treated diabetes in the United States who represent a disproportionately large share of the $B in direct medical costs attributable to diabetesThe use of continuous glucose monitoringCGMhas been shown to reduce HbA c levelsa proven predictor of health outcomes within this populationwith the greatest improvement achieved when CGM is cou ...

Abstract: Thoracotomy is one of the most painful surgical procedures and patients are at high risk of developing opioid addiction. Recent studies have shown 1 in 7 patients became new persistent opioid users after physical recovery from the surgery was complete. The largest risk factor for opioid addiction is being prescribed opioids in the first place, and Thermaquil wants to reduce this incidenc ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to enhance data security by solving the current problem of securing data in use through encryption. It has the potential to build trust on the cloud by overcoming the technical challenges of building a fully homomorphic encryption solution. This will allow data owners to encrypt their confi ...

PROJECT SUMMARY Osteogenesis imperfectaOIalso known asbrittle bone diseaseis a genetic disease in which patients have defects in the formationstructureor strength of their bonescausing them to break easilyOI patients exhibit impaired tissue development and bone regeneration due to inherited mutations in one of the collagen genesleading to skeletal defectsbone fragilitydentinogenesis imperfectahear ...

Project Summary Abstract Clinical decision supportCDSis a process for enhancing health related decisions and actions with pertinentorganized clinical knowledge and patient information to improve healthcare deliveryFor exampledoctors may have trouble remembering to order all guideline recommended care for sepsisCDS delivered via an order set in the electronic health recordEHRcan simplify this proce ...