You are here
Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
-
A Novel Microfludic Device for Drug Toxicity Studies
SBC: CFD RESEARCH CORPORATION Topic: CBD10103Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...
SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense -
Microfluidic High-throughput Platform for Determining of Kinetic Constants of Enzyme Variants
SBC: CFD RESEARCH CORPORATION Topic: CBD10107Molecular biology techniques allow generating combinatorial libraries of large number of enzyme variants. However, there is currently no technology available for screening the enzyme libraries for identifying variants with improved activity for the substrate. We propose to develop a novel, microfluidic, high-throughput platform for determining kinetic constants of enzyme variants and identifying v ...
SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense -
AC Impedance Sensor for Collective Protection Filter Residual Life Indicator
SBC: GUILD ASSOCIATES INC Topic: CBD10106Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...
SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense -
In vitro Models Suitable for High-throughput Screening of Drug Toxicities in Human Tissues
SBC: Nico Technologies Corp. Topic: CBD10103The drug R&D cycle is long and very expensive. In many ways, this status quo can no longer be sustained. One of the reasons for such great cost is that the vast majority of drug candidates are screened out at the stages of animal and human trials. More efficient methods of testing of drugs at the stage of ex-vivo studies, which are substantially less expensive than animal and human testing cyc ...
SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense -
Multifunctional Antisense Therapeutics Nanocarrier and Inhalation Device
SBC: Physical Optics Corporation Topic: CBD10102To address the CBD need for improved formulations to enhance the ease of use and bioavailability of antisense therapeutics, Physical Optics Corporation (POC) proposes to develop a Multifunctional Antisense Therapeutics Nanocarrier and Inhalation Device (MATEN). This proposed system is based on a new dry powder formulation and a novel design of an inhaler that uses in-house developed mature compone ...
SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense -
Miniature Residual Life Indicator
SBC: Physical Optics Corporation Topic: CBD10106Impregnated ASZM-TEDA carbon employed as highly adsorptive materials in Collective Protection (ColPro) systems loses the ability to adsorb toxic chemicals because of exposure to temperature, humidity, battlefield contaminants, and other pollutants. To address the Chemical and Biological Defense (CBD) need for a residual life indicator (RLI) capable of probing the degradation in physical adsorption ...
SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense -
3D Microfluidic Platform for in vitro Hematopoietic Stem Cell (HSC) Culture
SBC: Physical Optics Corporation Topic: CBD10103To address the Chemical/Bio Defense (CBD) need for in vitro models suitable for high-throughput screening of drug toxicities in human tissues, Physical Optics Corporation (POC) proposes to develop a new three-dimensional (3D) Microfluidic Platform for in-vitro Hematopoietic Stem Cell (HSC) Culture (3D-Mic-Stem). This proposed system is based on a 3D microfluidic design that uses HSCs for assaying ...
SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense -
Microfluidic Dielectrophoretic Screening System
SBC: Physical Optics Corporation Topic: CBD10107To address the U.S. Army/DTRA’s CBD program need for a robust screening process for use with large panels of enzymes to identify variants with higher affinity for organophosphorus (OP) substrates, Physical Optics Corporation (POC) proposes to develop a Microfluidic Dielectrophoretic Screening (MDS) system. This proposed system is based on the new design of a microfluidic mixer, enzymatic reactor ...
SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense -
An automated, high throughput, resin-free device for large scale protein purification
SBC: CFD RESEARCH CORPORATION Topic: CBD12102Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...
SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense -
A Novel, Aerodynamics-augmented Continuous Ionization System for Electrostatic Collection of Bioaerosols
SBC: CFD RESEARCH CORPORATION Topic: CBD12107Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...
SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense