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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Field Portable Mass Spectrometry for Small Molecule Drugs in Clinical Samples

    SBC: SPECTRAL ENERGIES LLC            Topic: CBD181006

    We propose a novel two-dimensional mass spectrometry (2D-MS) technique based on ion trap arrays to identify illicit and designer drugs. This approach will give an unprecedented multiplex advantage for miniature mass spectrometry, allowing novice field technicians to rapidly identify drugs affecting the central nervous system based on both the m/z ratio and fragmentation pattern of an ion. Towards ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  2. Dual Formulation of Atropine/Scopolamine with Enhanced Stability

    SBC: CMC PHARMACEUTICALS INC            Topic: CBD181005

    CMC Pharmaceuticals, Inc. (Cleveland, OH) is proposing developing a stable, combination product of two small molecule drug candidates as a counter measure to chemical warfare nerve agents (NA). The combination product is expected to exploit complementary pharmacological profiles for optimal muscarinic receptor blockade and anticholinergic activity within the peripheral and central nervous system. ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Host-Targeted Antiviral Drugs Providing Rapid, Scalable, Stable, Broad-Spectrum MedicalCountermeasure Against Marburg Virus

    SBC: EVRYS BIO LLC            Topic: CBD18A002

    In a pandemic or exposure to weaponized Marburg virus the morbidity, mortality and social unrest that will ensue before vaccines orMilitary operating on foreign soil as well as to the population of the US Homeland. Practically all threat agents of biological origin (except forcertain non-proteinaceous toxins, typically produced by marine organisms and fungi) have their structure and vital function ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  4. Circulating Diagnostic Markers of Infectious Disease

    SBC: PATHOVACS INCORPORATED            Topic: CBD18A001

    The focus of this STTR phase I component is on proof-of-concept studies demonstrating applicability of technical approaches for identificationof circulatory diagnostic markers for infectious disease. Therefore, the primary objective of this project is to determine feasibility of one suchtechnical approach called Proteomics-based Expression Library Screening (PELS), for identification of pathogen-d ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  5. Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious Diseases

    SBC: CFD RESEARCH CORPORATION            Topic: CBD18A001

    In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  6. Innovative Respiratory Protection for Low Threat Environments

    SBC: D. Wheatley Enterprises, Inc.            Topic: CBD181002

    Respiratory equipment has always required the use of a face seal or neck dam to provide good levels of protection. Although proven to beeffective, this approach is constraining when conceiving future integrated systems and can heavily burden the wearer. The development of anew device for lower threat environments, now provides the opportunity to finally remove the rubber off the face. This program ...

    SBIR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  7. Process Development and Manufacture of an Antibody-based Therapy Against Sudan EbolaVirus

    SBC: BIOFACTURA, INC.            Topic: CBD171005

    Recently we have observed a massive outbreak of Ebola virus. This family of virus causes a significant bioterrorism threat due to the high levelof mortality, rate of transmissibility and the lack of an approved vaccine or therapy directed against it. The goal of this proposal is to develop,optimize and scale-up a mammalian cell culture-based bioprocess for the rapid manufacture of an antibody-base ...

    SBIR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  8. AOTF-based Spectral Imaging for Enhanced Stand-off Chemical Detection

    SBC: DRS SCIENTIFIC, INC.            Topic: CBD13104

    DRS Scientific proposes a new type of Acousto-Optic Tuned Filter (AOTF) polarimetric hyperspectral imager that is compact, rugged, and inexpensive, has no moving parts, is free of optical aberrations, and is fast and sensitive. It will cover 8-12 mm with 8 cm-1 spectral resolution or finer, and will have mFlick sensitivity with a cooled camera, and

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  9. Development Of Low Cost Infrared Focal Plane Array For Passive Chemical Detection Using Colloidal Quantum Dots

    SBC: BRIMROSE TECHNOLOGY CORP            Topic: CBD13105

    We propose to develop low cost LWIR FPAs using colloidal quantum dots (CQDs) of II-VI semi-metallic compounds. Brimrose has experience in the area of II-VI semiconductor QD synthesis and LWIR detector fabrication using narrow band gap semiconductor materials. Research Triangle Institute (RTI) in NC has experience in building FPAs using CQDs, and to the best of our knowledge is the only institute ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  10. AOTF Based Spectro-Polarimetric Imaging System For Stand Off Chemical Detection

    SBC: BRIMROSE TECHNOLOGY CORP            Topic: CBD13104

    We propose an acousto-optic tunable filter (AOTF) spectropolarimetric imaging system for enhanced standoff chemical detection in the Long Wave Infrared (LWIR) wavelength region. The AOTF has no moving parts, making it a rugged and reliable device, and it provides polarimetric imaging capabilities, which enhances its chemical detection capabilities. We have been actively researching suitable mater ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
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