Award Data

Project Summary/Abstract Objective: This project aims to elevate electron beam therapy (EBT) technology, which provides effective radiation treatment for superficial cancers (depthandlt;6 cm), to that of other external beam radiotherapies (XRT), e.g. x-rays and protons, by bringing electron intensity modulation into the clinic. Challenge: Approximately 10% of radiotherapy patients (173,000 in U ...

The broader impact/commercial potential of this SBIR Phase I project is to develop a desalination system powered by solar energy. Water is used for lithium and rare metal mining, requiring energy-efficient water treatment to produce fresh water and concentrated brines. This type of water treatment in mineral recovery systems can yield valuable critical materials as byproducts. Many lithium and rar ...

PAProject Summary Abstract SERis a long acting polymer pro drug of buprenorphine that is being developed to treat postoperative pain following major surgeries such as bunionectomyabdominoplastythoracotomy and knee and hip surgerySERhas no biological activity by itselfbut when administered in vivo by subcutaneous injection it enters the vascular compartment where a plasma esterasebutyrylcholinester ...

The Air Force has a need for low-cost, short takeoff and landing vehicles to provide recovery and transport support in contested areas while minimizing the required number of operational personnel. An autonomous vehicle capable of 100 miles operational radius, cruise speed greater than 100 kts at 4000 ft, and takeoff/landing zone of 50 ft x 50 ft is desired to perform combat search and rescue, as ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to enhance data security by solving the current problem of securing data in use through encryption. It has the potential to build trust on the cloud by overcoming the technical challenges of building a fully homomorphic encryption solution. This will allow data owners to encrypt their confi ...

The broader/commercial impact of this SBIR phase II project will develop magnetic and fluorescent reagents for the separation and analysis of cells from tissue samples stored in biobanks, central repositories for biological samples, including tissues, cells, blood, sera, and urine, and their associated patient data, used in research to identify new methods to diagnose and treat disease; this indus ...

In the Phase II project, METSS will continue the development of a safe, robust, rapid, and effective chlorine dioxide (ClO2) gas dispersion system to be used for on-site room decontamination in hospital and non-hospital settings. The heart of the decontamination system is a proprietary ClO2 generating micro-reactor technology that is used to quickly and safely generate ClO2 on-site. This technolog ...

ABSTRACT SUMMARY In previous studies we identified novel non hematopoietic umbilical cord blood stem cellsnhUCBSCsthat could be expanded to high passages and exhibit restorative properties following ischemic brain injury repairWe found that the high passaged cells were equivalentif not even betterthan the low passaged nh UCBSCsThis finding suggests that these cells can serve as a source of highly ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to deliver state of the art cryptography and cybersecurity solutions to Internet of Things (IoTs) and embedded device designers, enterprise hardware and software vendors, and government contractors against the attack of classical and quantum computers. It has been widely accepted that quan ...

NIH SBIR PA-18-871 w/o Clinical Trials A Safe and Compact Neonate to Adult Neuroimaging MRI System The intriguing human brain is the most imaged end-organ non-invasively, without ionizing radiation using magnetic resonance imaging (MRI). High spatial resolution brain MRI is an established diagnostic tool to assess injury mechanisms affecting newborn growth and the adult human connectome. To predic ...