Award Data

DESCRIPTION provided by applicant Tuberculosis TB disease which results from infection with Mycobacterium tuberculosis Mtb is a leading cause of infectious morbidity and mortality in children andlt years old worldwide In TB endemic regions in which the vast majority of the worldandapos s annual million adult cases of TB disease reside children andlt years old account for ...

DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...

DESCRIPTION (provided by applicant): Sepsis is the tenth-leading cause of death in the United States and the second-leading cause of death in the intensive care unit (ICU). Sepsis kills over 215,000 Americans each year - more than breast cancer, lung cancer, and prostate cancer combined. Rapid identification and determination of antibiotic susceptibility is critical fo effective treatment of infec ...

DESCRIPTION provided by applicant Dramatic advances in the development of biomedical ontologies hold the promise of a deeper and clearer understanding of the molecular and genetic aspects that affect human health Biomedical data and knowledge stored in ontologies and databases have the potential to empower researchers in the life sciences to access and find conclusive evidence that can be translat ...

DESCRIPTION In this SBIR Phase II PicoCal will develop a high throughput apparatus to measure changes in cell adhesion at the level of individual receptor ligand interactions in real time This tool finds critical applications in research and drug development and would allow researchers to study and manipulate adhesion by bioactive compounds to promote or inhibit physiological processes There is a ...

DESCRIPTION provided by applicant Noroviruses are a group of enteropathogenic viruses belonging to the taxonomic family Caliciviridae which causes approximately of epidemic non bacterial outbreaks of gastroenteritis around the world and may be responsible for of all foodborne outbreaks of gastroenteritis in the US In developing countries according to a estimate by CDC researchers up to children le ...

DESCRIPTION provided by applicant Development of radiological nuclear medical countermeasures to treat Acute Radiation Syndrome ARS is a high priority research area for NIAID Bone marrow is one of the most sensitive tissues to radiation damage and impaired hematopoiesis is one of the first clinical signs of excessive radiation exposure often resulting i death Granulocyte colony stimulating ...

Concern has been raised over the prevalence of behavioral health disorders in military personnel returning from deployment to the Middle East. While not appearing as an overt physical injury, disruptions of a psychological nature are often as debilitating, and there is an increasing need for support tools. Such tools should allow for standardized tracking, monitoring, and mitigation of anger and ...

For this Phase II SBIR project, Vcom3D proposes a Serious Game for Continuity of Care that trains combat physicians in making critical medical decisions when faced with a multiple-casualty, multi-trauma incident. The Serious Game for Continuity of Care will provide a fast-paced learning environment that will require the selective attention to numerous, competing visual and aural cues and delegatio ...

This project aims to further develop the technology of frequency stabilized lasers for microwave generation, laser radar and other precision measurement applications. The goal is to decrease the noise floor of the stabilized laser to ~ 6 x 10^-16 at 1 s, and improve operational robustness to allow the device to be transported and operated at the Hz level in stand-alone operation, and mitigate the ...