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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A CD8+ T cell diagnostic to identify children with pulmonary tuberculosis

    SBC: ViTi, Inc            Topic: NIAID

    DESCRIPTION provided by applicant Tuberculosis TB disease which results from infection with Mycobacterium tuberculosis Mtb is a leading cause of infectious morbidity and mortality in children andlt years old worldwide In TB endemic regions in which the vast majority of the worldandapos s annual million adult cases of TB disease reside children andlt years old account for ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A cost-effective bioreactor to advance functional tissue engineering of cartilage

    SBC: APEX BIOMEDICAL COMPANY, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the leading cause of chronic disability in the United States. A clinical goal in the treatment and prevention of OA is to develop replacement cartilage using tissue engineering (TE) technologies. Although TE cartilage presently lacks the mechanical stability of native cartilage, studies have demonstrated that mechanical stability can be e ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Activity of Fully Deleted Helper-Virus Independent Adenoviral Gene Therapy Vector

    SBC: ISOGENIS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Numerous diseases are caused by gene defects. The goal of gene therapy is the effective treatment or cure of these diseases by the introduction of the normal gene or repair of the gene defect. A large research effort has been mounted to optimize gene transfer vectors mostly based on adenoviruses and retroviruses. Yet, the initial promise of gene therapy has bee ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  4. A custom microchip amplifier for patch clamp electrophysiological recording

    SBC: MAINSTREAM ENGINEERING CORPORATION            Topic: NIEHS

    DESCRIPTION: An estimated 2.5 billion people, or about one-third of the world's population, rely on biomass fuel for cooking. Emissions from biomass cook stoves contribute to global climate change, indoor/local air quality issues, and related health effects. In particular, indoor ir quality issues related to biomass cook stoves contribute significantly to rates of acute respiratory infection ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. ADAPT: After Deployment Adaptive Parenting Tools

    SBC: IRIS MEDIA INC            Topic: NICHD

    DESCRIPTION (provided by applicant): The goal of this project is to strengthen family functioning and improve child outcomes in military families after deployment. To achieve this end, we will develop, evaluate, and disseminate ADAPT: After Deployment: Adaptive Parenting Tools, an online, interactive resource for military parents. Significance: ADAPT responds to the urgent parenting needs of veter ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. ADAPT Online: After Deployment Adaptive Parenting Tools

    SBC: IRIS MEDIA INC            Topic: NICHD

    DESCRIPTION (provided by applicant): The goal of this Phase II project, ADAPT Online (After Deployment: Adaptive Parenting Tools), is to strengthen family functioning and improve child outcomes in reintegrating military families. By developing an empirically supported, standalone, web-based parenting intervention for military families with school-aged children, we expect to strengthen parenting pr ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. A Framework and Decision Tool for Confidentiality Protection in Public Use Data

    SBC: OPTIMIZATION TECHNOLOGIES, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): Statistical databases for public use pose a critical problem: how to make the data available for analysis without disclosing information that would infringe on privacy, violate confidentiality, or endanger national security. Organizations in the public and private sectors have a major stake in this confidentiality protection problem, given the fact that access ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  8. A Home Exercise Program (DVD) for Women with Infants and Young Children

    SBC: KLEIN BUENDEL, INC            Topic: NIDA

    DESCRIPTION (provided by applicant): Becoming a mother is a significant transition in a woman's life. This transition can precipitate major changes in health behaviors, like physical activity. Once a woman has a child she is much less likely to participate in regular, moderate to vigorous physical activity compared to women without children. Thus, new mothers are at risk for future weight gain and ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  9. A Low-Cost Upper-Extremity Prosthetic Interface

    SBC: ADA Technologies, Inc.            Topic: NICHD

    DESCRIPTION (provided by applicant): Remarkable advances in signal processing techniques, materials sciences, battery technologies, and computer-aided design and computer-aided manufacturing (CAD/CAM) processes have led to significant developments in assistive technologies. Coordinated research and commercialization have dramatically increased prosthetic function, utility, personalization, comfort ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Aluminum Oxide Nanoparticles Conjugated to Antigens Potently Induce Tumor Specifi

    SBC: UBIVAC, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): PROJECT SUMMARY Although prophylactic vaccines have potential for prevention of high risk human papilloma virus (HPV) infection they have no therapeutic efficacy. It has been estimated that there will be no measurable decline of HPV- associated tumors before 2040 (Hellner et al., 2011). Likewise, other HPV-associated angogenital and head and neck cancers are pr ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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