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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Accurate, long read length, whole human genome sequencing under 100

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): The aim of this project is to investigate a simple method for slowing down the rate of electrophoretic translocation of DNA through a nanopore. Unique modulations of current across nanopores produced by individual basesduring such translocation forms the basis of DNA nanopore sequencing. The nanopore method requires very simple sample preparation with potential ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A CD8+ T cell diagnostic to identify children with pulmonary tuberculosis

    SBC: ViTi, Inc            Topic: NIAID

    DESCRIPTION provided by applicant Tuberculosis TB disease which results from infection with Mycobacterium tuberculosis Mtb is a leading cause of infectious morbidity and mortality in children andlt years old worldwide In TB endemic regions in which the vast majority of the worldandapos s annual million adult cases of TB disease reside children andlt years old account for ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. A Comprehensive Platform to study drug interaction with physiologically important

    SBC: Optivia Biotechnology Inc.            Topic: NIMH

    CNS Transporters have crucial roles on neurophysiology and etiology. Inhibition of these critical transporters can have therapeutic benefits or cause serious side effects in the CNS. Development of an assay platform and a comprehensive profile of drugs' inhibitory effects on important CNS transporters can have enormous impact on drug discovery and development, such as elucidating drugs' ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. A cost-effective bioreactor to advance functional tissue engineering of cartilage

    SBC: Apex Biomedical Company, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the leading cause of chronic disability in the United States. A clinical goal in the treatment and prevention of OA is to develop replacement cartilage using tissue engineering (TE) technologies. Although TE cartilage presently lacks the mechanical stability of native cartilage, studies have demonstrated that mechanical stability can be e ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Activity of Fully Deleted Helper-Virus Independent Adenoviral Gene Therapy Vector

    SBC: ISOGENIS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Numerous diseases are caused by gene defects. The goal of gene therapy is the effective treatment or cure of these diseases by the introduction of the normal gene or repair of the gene defect. A large research effort has been mounted to optimize gene transfer vectors mostly based on adenoviruses and retroviruses. Yet, the initial promise of gene therapy has bee ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. A custom microchip amplifier for patch clamp electrophysiological recording

    SBC: MAINSTREAM ENGINEERING CORP            Topic: NIEHS

    DESCRIPTION: An estimated 2.5 billion people, or about one-third of the world's population, rely on biomass fuel for cooking. Emissions from biomass cook stoves contribute to global climate change, indoor/local air quality issues, and related health effects. In particular, indoor ir quality issues related to biomass cook stoves contribute significantly to rates of acute respiratory infection ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. ADAPT: After Deployment Adaptive Parenting Tools

    SBC: IRIS MEDIA INC            Topic: NICHD

    DESCRIPTION (provided by applicant): The goal of this project is to strengthen family functioning and improve child outcomes in military families after deployment. To achieve this end, we will develop, evaluate, and disseminate ADAPT: After Deployment: Adaptive Parenting Tools, an online, interactive resource for military parents. Significance: ADAPT responds to the urgent parenting needs of veter ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Adapting the SISTA/SIHLE/WILLOW HIV Prevention Trilogy for Black Men Who Have Sex

    SBC: Sociometrics Corporation            Topic: NIMHD

    DESCRIPTION (provided by applicant): Black men who have sex with men (MSM) have been disproportionately affected by the HIV/AIDS epidemic in the United States. Yet, there are very few scientifically demonstrated effective HIV prevention interventions targeting Black MSM. This SBIR Phase I project will address this gap by creating an adaptation kit to support the delivery of the popular SISTA/SIHLE ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Adapting the SiSTA/SiHLE/WiLLOW Prevention Trilogy for Black Men

    SBC: Sociometrics Corporation            Topic: NIMHD

    DESCRIPTION provided by applicant Adapting the SISTA SiHLE WiLLOW HIV Prevention Trilogy for Black Men Who Have Sex with Men MSM Black men who have sex with men MSM have been disproportionately affected by HIV AIDS since the beginning of the epidemic Yet there are very few scientifically demonstrated effective HIV prevention interventions targeting Black MSM This SBIR Phase II project ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Adaptive Data Visualization and Optimally Relevant Interface System

    SBC: Physical Optics Corporation            Topic: SB101006

    To address the DARPA Information Processing Techniques Office (IPTO) need for solutions that enable on-the-fly geospatial visualization on devices and systems with disparate display resolutions and connection bandwidths, Physical Optics Corporation (POC) proposes to develop a new Adaptive Data Visualization and Optimally Relevant Interface (ADVISOR) system based on a new method of visualization th ...

    SBIR Phase I 2010 Department of DefenseDefense Advanced Research Projects Agency
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