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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Lead compound discovery from proprietary mycobacterial strains for treatment of PTSD
SBC: MYCOBACTERIA THERAPEUTICS CORPORATION Topic: NCCIHProject Summary Immunoregulation, i.e., balanced expression of regulatory and effector T cells, is thought to be compromised in modern high-income settings due in part to reduced contact with commensal and environmentally derived bacteria, also known as “old friends”. Failed immunoregulation is thought to be one factor contributing to recent increases in stress-related and chronic inflammatory ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Commercialization of SciDAP, a next generation universal platform for collaborative data analysis
SBC: DATIRIUM LLC Topic: NHGRISummary The recent proliferation of next-generation sequencing (NGS) - based methods for the analysis of gene expression, chromatin structure and protein-DNA interactions has created tremendous opportunities for gaining novel insights into basic biology, health, and disease. However, analysis of the resulting data requires computational expertise that many traditional biologists do not possess. He ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Development of a topical fixed-dose combination drug for peripheral neuropathic pain.
SBC: WinSanTor, Inc. Topic: NINDSPROJECT SUMMARY An estimated 30 million people in the United States suffer from some form of peripheral neuropathy, a condition that develops as a result of damage to the peripheral nervous system. The top two major causes of peripheral neuropathy in the US are diabetes mellitus (both T1DM and T2DM) and chemotherapeutic agents. Currently, there are no FDA-approved treatments to prevent or reverse ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Image Analysis Tools for mpMRI Prostate Cancer Diagnosis Using PI-RADS
SBC: Eigen Health Services LLC Topic: 102Project Summary Prostate cancer is one of the most commonly occurring forms of cancer, accounting for 21% of all cancer in men. The Prostate Imaging Reporting and Data System (PI-RADS) aims to standardize reporting of prostate cancer using multi-parametric magnetic resonance imaging (mpMRI). However, the in-depth analysis, as demanded by PI-RADS, remains challenging due to the complexity and heter ...
STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
Enabling self-reported outcomes for youth with developmental disabilities: The PediatricEvaluation of Disability Inventory- Patient Reported Outcome (PEDI-PRO)- Phase II
SBC: ABLELINK TECHNOLOGIES INC Topic: NICHDThe lack of patient reported outcome measures (PROMs) appropriate for youth with neurodevelopmental disabilities (DD) and related cognitive impairments including Down syndrome (DS) poses a significant problem for healthcare research and practice. Parents and other professionals do not identify the same needs as youth, and failure to engage youth with DD in healthcare evaluation compromises healthc ...
STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
The Development and Systematic Evaluation of an AI-Assisted Just-in-Time-Adaptive-Intervention for Improving Child Mental Health
SBC: Colliga Apps Corp. Topic: 104PROJECT SUMMARY/ABSTRACT Early childhood mental health problems constitute a significant public health concern with wide-ranging impacts on functioning both concurrently and later in life. Although childhood mental health is influenced by a variety of factors, the quality of relationships with caregivers plays a critical role. Critical, coercive, and conflictual parent- child interactions have bee ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
FH-Fc as a Pre-Exposure Prophylactic for Tickborne Disease
SBC: Planet Biotechnology Incorporated Topic: NIAIDLyme disease (LD) is the most prevalent vector-borne disease in the United States, with up to 300,000 cases a year. LD is caused by several species of the spirochete bacteria Borrelia burgdorferi sensu lato (the Lyme borreliae), which are transmitted by ticks from animal (bird, rodent) reservoirs to human hosts. While a short course of antibiotics is usually effective in eliminating the bacteria a ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Development of a Caregiver Application and AI-Enabled Intelligent Assistant to Support Families and Formal Care Providers in Caring for Persons with Alzheimer's Disease and Related Dementias
SBC: Whiplash Technology, Inc. Topic: NIAPROJECT ABSTRACT Family caregivers face daunting challenges in caring for persons with Alzheimer’s disease. Currently, there is no widely available mechanism to provide real-time, context sensitive support to informal AD caregivers that can address the specific care needs of each AD patient. To address this critical gap, we developed CareVirtue, an innovative web/mobile application for family ca ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Development of Spleen Tyrosine Kinase (SYK) negative allosteric modifiers for therapeutic intervention in Alzheimer's disease.
SBC: ARCHER PHARMACEUTICALS, INC. Topic: NIAPathological hallmarks of Alzheimerandapos;s disease (AD) include extracellular deposits of Aβ peptides, intraneuronal aggregates of abnormally phosphorylated tau protein and neuroinflammation. Most proposed AD disease modifying therapies have focused on strategies that reduce brain Aβ/amyloid or tau pathological accumulation. However, such approaches have been unsuccessful in late stage AD clin ...
STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
Engineering a unique antibody for patients with RA
SBC: ABWIZ BIO INC Topic: NIAIDRA is one of the most common chronic autoimmune disorders that can lead to complete joint destruction and severe disability if untreated. There is no cure for RA and up to 50% of RA patients do not respond to anti-TNF therapies as circulating Th-17/IL-17 levels are highly elevated subsequent to TNF blockade. For this subset of RA patients, disruption of a novel pathway that impairs the synergy bet ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health